The Sumo-targeted ubiquitin ligase RNF4 regulates the localization and function of the HTLV-1 oncoprotein Tax

The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks

(2011) Caitlin E. Cook et al.   CELL CYCLE

Ubiquitin-Specific Peptidase 20 Targets TRAF6 and Human T Cell Leukemia Virus Type 1 Tax To Negatively Regulate NF- B Signaling

(2011) J. Yasunaga et al.   JOURNAL OF VIROLOGY

HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes

(2010) M. Bellon et al.   BLOOD

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

(2010) Y. Kfoury et al.   BLOOD

SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor

(2010) Y. Xie et al.   GENES & DEVELOPMENT

The Viral Oncoprotein Tax Sequesters DNA Damage Response Factors by Tethering MDC1 to Chromatin

(2010) S. Mehdi Belgnaoui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SUMO protease SENP6 is essential for inner kinetochore assembly

(2010) Debaditya Mukhopadhyay et al.   JOURNAL OF CELL BIOLOGY

PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

(2009) P. Yan et al.   BLOOD

PARP-1 transcriptional activity is regulated by sumoylation upon heat shock

(2009) Nadine Martin et al.   EMBO JOURNAL

Dimerization and a Novel Tax Speckled Structure Localization Signal Are Required for Tax Nuclear Localization

(2009) K. A. Fryrear et al.   JOURNAL OF VIROLOGY

Quality Control of a Transcriptional Regulator by SUMO-Targeted Degradation

(2009) Z. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

RNF4 and VHL regulate the proteasomal degradation of SUMO-conjugated Hypoxia-Inducible Factor-2α

(2009) Martijn van Hagen et al.   NUCLEIC ACIDS RESEARCH

HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase

(2008) Sarah S. Durkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

A SIM-ultaneous role for SUMO and ubiquitin

(2008) J. Jefferson P. Perry et al.   TRENDS IN BIOCHEMICAL SCIENCES