Molecular Pathogenesis of MALT Lymphoma

Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2–MALT1 in MALT lymphoma

(2015) Zilin Nie et al.   Nature Communications

FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF- B to promote survival of human B cells

(2014) M. van Keimpema et al.   BLOOD

Targeting pathological B cell receptor signalling in lymphoid malignancies

(2013) Ryan M. Young et al.   NATURE REVIEWS DRUG DISCOVERY

B-cell receptor signaling as a driver of lymphoma development and evolution

(2013) Carsten U. Niemann et al.   SEMINARS IN CANCER BIOLOGY

MYD88 somatic mutations in MALT lymphomas

(2012) Zhi-Ming Li et al.   BRITISH JOURNAL OF HAEMATOLOGY

Chlamydophila PsittaciEradication With Doxycycline As First-Line Targeted Therapy for Ocular Adnexae Lymphoma: Final Results of an International Phase II Trial

(2012) Andrés J.M. Ferreri et al.   JOURNAL OF CLINICAL ONCOLOGY

Chemokine receptors in gastric MALT lymphoma: loss of CXCR4 and upregulation of CXCR7 is associated with progression to diffuse large B-cell lymphoma

(2012) Alexander JA Deutsch et al.   MODERN PATHOLOGY

MALT1 Protease: A New Therapeutic Target in B Lymphoma and Beyond?

(2011) L. M. McAllister-Lucas et al.   CLINICAL CANCER RESEARCH

A20 inactivation in ocular adnexal MALT lymphoma

(2011) Y. Bi et al.   HAEMATOLOGICA

MALT lymphoma: many roads lead to nuclear factor-κb activation

(2011) Ming-Qing Du   HISTOPATHOLOGY

Chlamydia psittaciInfection in Nongastrointestinal Extranodal MALT Lymphomas and Their Precursor Lesions

(2010) Ariane Aigelsreiter et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Clinical activity of bortezomib in relapsed/refractory MALT lymphomas: results of a phase II study of the International Extranodal Lymphoma Study Group (IELSG)

(2010) A. Conconi et al.   ANNALS OF ONCOLOGY

Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome

(2010) A. Rinaldi et al.   BLOOD

Oncogenically active MYD88 mutations in human lymphoma

(2010) Vu N. Ngo et al.   NATURE

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

(2010) R. Eric Davis et al.   NATURE

E -BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF- B pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma

(2009) Z. Li et al.   BLOOD

The NF- B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas

(2009) U. Novak et al.   BLOOD

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

(2009) K. Honma et al.   BLOOD

A phase II study of bortezomib in patients with MALT lymphoma

(2009) M. Troch et al.   HAEMATOLOGICA

A20 is targeted by promoter methylation, deletion and inactivating mutation in MALT lymphoma

(2009) E Chanudet et al.   LEUKEMIA

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

Primary Cutaneous Marginal Zone B-Cell Lymphomas Are Targeted by Aberrant Somatic Hypermutation

(2008) Alexander J.A. Deutsch et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Distinct signatures of B-cell homeostatic and activation-dependent chemokine receptors in the development and progression of extragastric MALT lymphomas

(2008) AJA Deutsch et al.   JOURNAL OF PATHOLOGY

A20deletion is associated with copy number gain at theTNFA/B/Clocus and occurs preferentially in translocation-negative MALT lymphoma of the ocular adnexa and salivary glands

(2008) E Chanudet et al.   JOURNAL OF PATHOLOGY

Quantifying the role of aberrant somatic hypermutation in transformation of follicular lymphoma

(2008) Anna Margrét Halldórsdóttir et al.   LEUKEMIA RESEARCH

Two levels of protection for the B cell genome during somatic hypermutation

(2008) Man Liu et al.   NATURE

Oncogenic CARD11 Mutations in Human Diffuse Large B Cell Lymphoma

(2008) G. Lenz et al.   SCIENCE

TNFAIP3is the target gene of chromosome band 6q23.3-q24.1 loss in ocular adnexal marginal zone B cell lymphoma

(2007) Keiichiro Honma et al.   GENES CHROMOSOMES & CANCER

Chlamydia psittaci in MALT lymphomas of ocular adnexals: The Austrian experience

(2007) Ariane Aigelsreiter et al.   LEUKEMIA RESEARCH