14-3-3 and aggresome formation: Implications in neurodegenerative diseases

Parkin-mediated K63-linked polyubiquitination: A signal for targeting misfolded proteins to the aggresome-autophagy pathway

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Regulatory Coordination between Two Major Intracellular Homeostatic Systems

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14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes

(2013) Z. Xu et al.   JOURNAL OF CELL SCIENCE

The role of autophagy in neurodegenerative disease

(2013) Ralph A Nixon   NATURE MEDICINE

Stabilization and Inhibition of Protein–Protein Interactions: The 14-3-3 Case Study

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BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

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Protein kinase CK2 regulates the formation and clearance of aggresomes in response to stress

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Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins

(2011) Martin Gamerdinger et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes

(2011) Xingqian Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Colocalization of 14-3-3 Proteins with SOD1 in Lewy Body-Like Hyaline Inclusions in Familial Amyotrophic Lateral Sclerosis Cases and the Animal Model

(2011) Yoko Okamoto et al.   PLoS One

14-3-3 proteins in neurodegeneration

(2011) Petra Steinacker et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

14-3-3 proteins as potential therapeutic targets

(2011) Jing Zhao et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy

(2010) Lih-Shen Chin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Chaperone-mediated autophagy in protein quality control

(2010) Esperanza Arias et al.   CURRENT OPINION IN CELL BIOLOGY

Cellular strategies for controlling protein aggregation

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Heat shock proteins: Cellular and molecular mechanisms in the central nervous system

(2010) R. Anne Stetler et al.   PROGRESS IN NEUROBIOLOGY

Biological and Chemical Approaches to Diseases of Proteostasis Deficiency

(2009) Evan T. Powers et al.   Annual Review of Biochemistry

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

The role of molecular chaperones in human misfolding diseases

(2009) Sarah A. Broadley et al.   FEBS LETTERS

Aggresome Formation and Neurodegenerative Diseases: Therapeutic Implications

(2008) L. Chin et al.   CURRENT MEDICINAL CHEMISTRY

Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery

(2008) Yan Wang et al.   FASEB JOURNAL

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

14-3-3zeta is indispensable for aggregate formation of polyglutamine-expanded huntingtin protein

(2007) Kazuya Omi et al.   NEUROSCIENCE LETTERS