Regulatory Coordination between Two Major Intracellular Homeostatic Systems

A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy

(2014) Randy Singh Atwal et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Exercise induces autophagy in peripheral tissues and in the brain

(2012) Congcong He et al.   Autophagy

Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells

(2012) Ying-Hui Ko et al.   CANCER BIOLOGY & THERAPY

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy

(2012) Kristan E. van der Vos et al.   NATURE CELL BIOLOGY

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY

Arsenite-induced autophagy is associated with proteotoxicity in human lymphoblastoid cells

(2012) Alicia M. Bolt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Knockdown of insulin receptor substrate 1 reduces proliferation and downregulates Akt/mTOR and MAPK pathways in K562 cells

(2011) João Agostinho Machado-Neto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inhibition of glutamine-dependent autophagy increases t-PA production in CHO Cell fed-batch processes

(2011) Mario A. Jardon et al.   BIOTECHNOLOGY AND BIOENGINEERING

Autophagy inhibition through PI3K/Akt increases apoptosis by sodium selenite in NB4 cells

(2011) Yun Ren et al.   BMB Reports

The influence of mTOR on T helper cell differentiation and dendritic cell function

(2011) Robert J. Salmond et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Central Role for mTOR Kinase in Homeostatic Proliferation Induced CD8+ T Cell Memory and Tumor Immunity

(2011) Qingsheng Li et al.   IMMUNITY

α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes

(2011) Yong Zhang et al.   Lipids in Health and Disease

mTOR Controls Ovarian Follicle Growth by Regulating Granulosa Cell Proliferation

(2011) James Yu et al.   PLoS One

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Negative regulation of autophagy

(2010) C Liang   CELL DEATH AND DIFFERENTIATION

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

LPS-induced cytokine levels are repressed by elevated expression of HSP70 in rats: possible role of NF-κB

(2010) Karol Dokladny et al.   CELL STRESS & CHAPERONES

The UPR and cell fate at a glance

(2010) P. I. Merksamer et al.   JOURNAL OF CELL SCIENCE

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

(2010) H. Hirai et al.   MOLECULAR CANCER THERAPEUTICS

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Modulation of Akt and ERK1/2 Pathways by Resveratrol in Chronic Myelogenous Leukemia (CML) Cells Results in the Downregulation of Hsp70

(2010) Soumyajit Banerjee Mustafi et al.   PLoS One

HSP72 Protects Cells from ER Stress-induced Apoptosis via Enhancement of IRE1α-XBP1 Signaling through a Physical Interaction

(2010) Sanjeev Gupta et al.   PLOS BIOLOGY

Glutamine attenuates acute lung injury by inhibition of high mobility group box protein-1 expression during sepsis

(2009) Woon Yong Kwon et al.   BRITISH JOURNAL OF NUTRITION

Control of autophagy initiation by phosphoinositide 3-phosphatase jumpy

(2009) Isabelle Vergne et al.   EMBO JOURNAL

The IKK complex contributes to the induction of autophagy

(2009) Alfredo Criollo et al.   EMBO JOURNAL

Facilitating Akt Clearance via Manipulation of Hsp70 Activity and Levels

(2009) John Koren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian macroautophagy at a glance

(2009) B. Ravikumar et al.   JOURNAL OF CELL SCIENCE

Cellular and Molecular Mechanisms of Heat Stress-Induced Up-Regulation of Occludin Protein Expression

(2008) Karol Dokladny et al.   AMERICAN JOURNAL OF PATHOLOGY

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins

(2008) Sami Reijonen et al.   EXPERIMENTAL CELL RESEARCH

Glutamine Increases Autophagy Under Basal and Stressed Conditions in Intestinal Epithelial Cells

(2008) Toshio Sakiyama et al.   GASTROENTEROLOGY

Lack of cross-tolerance following heat and cadmium exposure in functional MDCK monolayers

(2008) Karol Dokladny et al.   JOURNAL OF APPLIED TOXICOLOGY

OSU-03012 Stimulates PKR-Like Endoplasmic Reticulum-Dependent Increases in 70-kDa Heat Shock Protein Expression, Attenuating Its Lethal Actions in Transformed Cells

(2008) M. A. Park et al.   MOLECULAR PHARMACOLOGY

Regulation of autophagy by cytoplasmic p53

(2008) Ezgi Tasdemir et al.   NATURE CELL BIOLOGY

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PI3K/Akt: getting it right matters

(2008) T F Franke   ONCOGENE