Synthetic spirocyclic endoperoxides: new antimalarial scaffolds

Recent Approaches to Chemical Discovery and Development Against Malaria and the Neglected Tropical Diseases Human African Trypanosomiasis and Schistosomiasis

(2014) Mathew Njoroge et al.   CHEMICAL REVIEWS

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Pumped up: reflections on PfATP6 as the target for artemisinins

(2013) Sanjeev Krishna et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Synthetic Peroxides as Potent Antimalarials. News and Views

(2012) Charles W. Jefford   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A synthetic strategy to bridged 2,3,8-trioxabicyclo[3,3,1]nonane endoperoxides

(2012) Sandra Gemma et al.   TETRAHEDRON LETTERS

Cross-Metathesis Reactions of Homoallyl Methyl Malonates with Sterically Hindered Allylic Esters

(2011) Fabio Barile et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Comparison of the Reactivity of Antimalarial 1,2,4,5-Tetraoxanes with 1,2,4-Trioxolanes in the Presence of Ferrous Iron Salts, Heme, and Ferrous Iron Salts/Phosphatidylcholine

(2011) Fatima Bousejra-El Garah et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antiplasmodial Activity of Bicyclic Dioxanes as Simplified Dihydroplakortin Analogues

(2011) Sandra Gemma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Dihydroplakortin, 6-epi-Dihydroplakortin, and Their C10-Desethyl Analogues

(2010) Sandra Gemma et al.   JOURNAL OF ORGANIC CHEMISTRY

Insight into the mechanism of action of plakortins, simple 1,2-dioxaneantimalarials

(2009) Orazio Taglialatela-Scafati et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthetic studies toward 1,2-dioxanes as precursors of potential endoperoxide-containing antimalarials

(2009) Sandra Gemma et al.   TETRAHEDRON LETTERS