Synthesis of six mexiletine derivatives with isoindolines attached as potential antioxidants and their evaluation as cardioprotective agents

Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonist

(2014) C. Valant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exogenous glutathione is essential in the testing of antioxidant capacity using radical-induced haemolysis

(2012) Nitya Jani et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Edaravone containing isoindoline nitroxides for the potential treatment of cardiovascular ischaemia

(2011) James R. Walker et al.   MedChemComm

Hydroxylated Analogs of Mexiletine as Tools for Structural-Requirements Investigation of the Sodium Channel Blocking Activity

(2010) Alessia Catalano et al.   ARCHIV DER PHARMAZIE

A Novel Highly Selective Adenosine A1 Receptor Agonist VCP28 Reduces Ischemia Injury in a Cardiac Cell Line and Ischemia–Reperfusion Injury in Isolated Rat Hearts at Concentrations That Do Not Affect Heart Rate

(2010) Vijay B Urmaliya et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Design and Assessment of a Potent Sodium Channel Blocking Derivative of Mexiletine for Minimizing Experimental Neuropathic Pain in Several Rat Models

(2009) Robert M. Weston et al.   NEUROCHEMICAL RESEARCH

Experimental and Theoretical Studies of the Redox Potentials of Cyclic Nitroxides

(2008) James P. Blinco et al.   JOURNAL OF ORGANIC CHEMISTRY