C1–C2-linker substituted 1,5-naphthyridine analogues of oxabicyclooctane-linked NBTIs as broad-spectrum antibacterial agents (part 7)

Structure activity relationship of substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-4)

(2015) Sheo B. Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5)

(2015) Sheo B. Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6)

(2015) Sheo B. Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2)

(2015) Sheo B. Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3)

(2015) Sheo B. Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Determination of Disk Diffusion and MIC Quality Control Guidelines for GSK2140944, a Novel Bacterial Type II Topoisomerase Inhibitor Antimicrobial Agent

(2014) J. E. Ross et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Novel Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Potent Anti-Gram Positive Activity and Improved Safety Profile

(2014) Jean-Philippe Surivet et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxabicyclooctane-Linked Novel Bacterial Topoisomerase Inhibitors as Broad Spectrum Antibacterial Agents

(2014) Sheo B. Singh et al.   ACS Medicinal Chemistry Letters

Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases

(2013) Timothy J. Miles et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel quinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV

(2013) Mark J. Mitton-Fry et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design, Synthesis, and Characterization of Novel Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Potent Anti-Gram-Positive Activity

(2013) Jean-Philippe Surivet et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced pKa: Antibacterial Agents with an Improved Safety Profile

(2012) Folkert Reck et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases

(2011) Timothy J. Miles et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases

(2011) Timothy J. Miles et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity

(2011) Folkert Reck et al.   JOURNAL OF MEDICINAL CHEMISTRY

Type IIA topoisomerase inhibition by a new class of antibacterial agents

(2010) Benjamin D. Bax et al.   NATURE

Mechanism of Action of the Antibiotic NXL101, a Novel Nonfluoroquinolone Inhibitor of Bacterial Type II Topoisomerases

(2008) M. T. Black et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY