Decorated 6,6′,7,7′-tetrahydro-1H,1′H-2,3′-biindole scaffold as promising candidate for recognition of the CDK2 allosteric site

Direct synthesis of C3-mono-functionalized oxindoles from N-unprotected 2-oxindole and their antileishmanial activity

(2013) Angela Scala et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Self-Catalyzed Mannich-Type Reaction of Enolizable Cyclic 1,3-Dicarbonyls to Acyclic Nitrones: An Entry to Functionalized β-Enamino Diones

(2013) Massimiliano Cordaro et al.   JOURNAL OF ORGANIC CHEMISTRY

An in silico exploration of the interaction mechanism of pyrazolo[1,5-a]pyrimidine type CDK2 inhibitors

(2013) Yan Li et al.   Molecular BioSystems

Aldol-type compounds from water-soluble indole-3,4-diones: synthesis, kinetics, and antiviral properties

(2013) Angela Scala et al.   MOLECULAR DIVERSITY

PDB_REDO: constructive validation, more than just looking for errors

(2012) Robbie P. Joosten et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ATP Non-Competitive Ser/Thr Kinase Inhibitors as Potential Anticancer Agents

(2012) Giorgio Cozza et al.   Anti-Cancer Agents in Medicinal Chemistry

Overexpression of cyclin E/CDK2 complexes overcomes FGF-induced cell cycle arrest in the presence of hypophosphorylated Rb proteins

(2012) Victoria Kolupaeva et al.   CELL CYCLE

Optimization of parameters for semiempirical methods VI: more modifications to the NDDO approximations and re-optimization of parameters

(2012) James J. P. Stewart   JOURNAL OF MOLECULAR MODELING

Diastereoselective multicomponent synthesis and anti-HSV-1 evaluation of dihydrofuran-fused derivatives

(2012) Angela Scala et al.   MOLECULAR DIVERSITY

Discovery of a Potential Allosteric Ligand Binding Site in CDK2

(2011) Stephane Betzi et al.   ACS Chemical Biology

Synthesis and biological evaluation of 2,3-bis(het)aryl-4-azaindole derivatives as protein kinase inhibitors

(2011) Frédéric Pin et al.   MedChemComm

N-Substituted and N-unsubstituted 1,3-Oxazolium-5-olates cycloaddition reactions with 3-substituted coumarins

(2010) Massimiliano Cordaro et al.   TETRAHEDRON

Regio and diastereoselective synthesis of functionalized 2,3-dihydrofuro[3,2-c]coumarins via a one-pot three-component reaction

(2010) Elisa Altieri et al.   TETRAHEDRON

Stereodefined ring contraction-rearrangement of thiocoumarins to new fused benzo[b]thiophene derivatives

(2010) Massimiliano Cordaro et al.   TETRAHEDRON

Synthesis and anti HSV-1 evaluation of novel indole-3,4-diones

(2010) Angela Scala et al.   MedChemComm

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: Design and synthesis of a potent and isoform selective PKC-ζ inhibitor

(2008) John I. Trujillo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Progress in the evaluation of CDK inhibitors as anti-tumor agents

(2008) C MCINNES   DRUG DISCOVERY TODAY