Imaging of drug and metabolite distribution by MS: case studies

Evaluation of Therapeutics in Three-Dimensional Cell Culture Systems by MALDI Imaging Mass Spectrometry

(2013) Xin Liu et al.   ANALYTICAL CHEMISTRY

Evaluation of an Accurate Mass Approach for the Simultaneous Detection of Drug and Metabolite Distributions via Whole-Body Mass Spectrometric Imaging

(2012) Sheerin K. Shahidi-Latham et al.   ANALYTICAL CHEMISTRY

Central Nervous System Disposition and Metabolism of Fosdevirine (GSK2248761), a Non-Nucleoside Reverse Transcriptase Inhibitor: An LC-MS and Matrix-Assisted Laser Desorption/Ionization Imaging MS Investigation into Central Nervous System Toxicity

(2012) Stephen Castellino et al.   CHEMICAL RESEARCH IN TOXICOLOGY

In Situ Mass Spectrometry Imaging and Ex Vivo Characterization of Renal Crystalline Deposits Induced in Multiple Preclinical Drug Toxicology Studies

(2012) Anna Nilsson et al.   PLoS One

Quantitative analysis of pharmaceutical drug distribution in multiple organs by imaging mass spectrometry

(2012) Nozomi Takai et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Direct Demonstration of Tissue Uptake of an Inhaled Drug: Proof-of-Principle Study Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging

(2011) Thomas E. Fehniger et al.   ANALYTICAL CHEMISTRY

High-Sensitivity MALDI-MRM-MS Imaging of Moxifloxacin Distribution in Tuberculosis-Infected Rabbit Lungs and Granulomatous Lesions

(2011) Brendan Prideaux et al.   ANALYTICAL CHEMISTRY

Distribution of chloroquine in ocular tissue of pigmented rat using matrix-assisted laser desorption/ionization imaging quadrupole time-of-flight tandem mass spectrometry

(2011) Yasuhiro Yamada et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example

(2011) Daniel Eikel et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Matrix-assisted laser desorption mass spectrometry imaging for the examination of imipramine absorption by Straticell-RHE-EPI/001 an artificial model of the human epidermis

(2011) Jennie L. Avery et al.   XENOBIOTICA

MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

(2011) Stephen Castellino et al.   Bioanalysis

Correlation of Skin Blanching and Percutaneous Absorption for Glucocorticoid Receptor Agonists by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and Liquid Extraction Surface Analysis with Nanoelectrospray Ionization Mass Spectrometry

(2010) Peter Marshall et al.   ANALYTICAL CHEMISTRY

Utility of quantitative whole-body autoradiography (QWBA) and imaging mass spectrometry (IMS) by matrix-assisted laser desorption/ionization (MALDI) in the assessment of ocular distribution of drugs

(2010) Dieter M. Drexler et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Matrix-Assisted Laser Desorption/Ionization-Ion Mobility Separation-Mass Spectrometry Imaging of Vinblastine in Whole Body Tissue Sections

(2008) Paul J. Trim et al.   ANALYTICAL CHEMISTRY