Article
Multidisciplinary Sciences
Takafumi Shigehira, Tadashi Hanafusa, Kazuyo Igawa, Tomonari Kasai, Shuichi Furuya, Hisakazu Nishimori, Yoshinobu Maeda, Hiroyuki Michiue, Atsushi Fujimura
Summary: Boron neutron capture therapy (BNCT) is a radiation therapy that selectively kills cancer cells using the boron neutron capture reaction. The delivery dose of boron B-10 for anti-tumor effects in boron drugs is approximately 15-40 ppm, but its requirement for different boron drugs with different accumulation characteristics has not been extensively investigated.
ADVANCED THEORY AND SIMULATIONS
(2023)
Article
Medicine, Research & Experimental
Jelena Matovic, Katayun Bahrami, Philipp Stockmann, Iris K. . Sokka, You Cheng Khng, Mirkka Sarparanta, Evamarie Hey-Hawkins, Jarkko Rautio, Filip S. Ekholm
Summary: Boron neutron capture therapy (BNCT) is a cancer treatment that uses boron delivery agents to selectively eradicate tumor cells. In this study, we focus on a GLUT1-targeting strategy to BNCT and synthesize carborane-bearing D-galactose, D-mannose, and D-allose as potential delivery agents. We find that these agents exhibit significantly improved boron delivery capacity compared to clinically approved agents in vitro, laying the groundwork for future preclinical assessment studies.
MOLECULAR PHARMACEUTICS
(2023)
Review
Medicine, Research & Experimental
Ting Luo, Wenzhi Huang, Feiyi Chu, Tianyu Zhu, Bin Feng, Shuai Huang, Jing Hou, Liyong Zhu, Shaihong Zhu, Wenbin Zeng
Summary: Cancer is a devastating disease that requires intelligent diagnostic techniques, targeted treatments, and early prognosis evaluation for effective and personalized therapy. Boron neutron capture therapy (BNCT) has emerged as a promising approach for cancer treatment with unprecedented precision. However, the clinical application of BNCT technology faces challenges due to the limitations of current drugs. Therefore, there is an urgent need to develop efficient boron agents with higher boron content and specific tumor-targeting properties.
MOLECULAR PHARMACEUTICS
(2023)
Article
Biochemistry & Molecular Biology
Sebastian Flieger, Mao Takagaki, Natsuko Kondo, Marlon R. Lutz, Yash Gupta, Hiroki Ueda, Yoshinori Sakurai, Graham Moran, Prakasha Kempaiah, Narayan Hosmane, Minoru Suzuki, Daniel P. Becker
Summary: New carborane-bearing hydroxamate matrix metalloproteinase (MMP) ligands with nanomolar potency against MMP-2, -9 and -13 have been synthesized for boron neutron capture therapy (BNCT). In vitro studies showed that these new MMP ligands had high tumoricidal effects in the BNCT assay. This study highlights the importance of targeting MMP enzymes overexpressed on the surface of tumor cells for BNCT efficacy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Cell Biology
Jing Xiang, Lin Ma, Zheng Gu, Hongjun Jin, Hongbin Zhai, Jianfei Tong, Tianjiao Liang, Juan Li, Qiushi Ren, Qi Liu
Summary: There is a need for improved treatment modality for glioblastoma due to its resistance to traditional chemoradiation therapy. Boron neutron capture therapy (BNCT) combined with temozolomide chemotherapy shows promising potential for glioblastoma treatment.
Review
Oncology
Tainah Dorina Marforio, Andrea Carboni, Matteo Calvaresi
Summary: This review provides an overview of the applications of carboranes in in vivo BNCT studies, including the use of different molecules, formulation and administration strategies, investigation of tumor models, and qualitative and quantitative methodologies for carborane detection in in vivo experiments.
Review
Medicine, Research & Experimental
Qi Dai, QiYao Yang, Xiaoyan Bao, Jiejian Chen, Min Han, Qichun Wei
Summary: Boron neutron capture therapy (BNCT) is a promising biological targeted technique for cancer therapy, with good targeting and high effectiveness. It causes less damage to surrounding healthy tissue compared to other methods. Measuring boron concentration is crucial but current technology falls short. This review discusses the development of methods and imaging to improve measurement accuracy.
MOLECULAR PHARMACEUTICS
(2022)
Review
Medicine, Research & Experimental
Qi Dai, QiYao Yang, Xiaoyan Bao, Jiejian Chen, Min Han, Qichun Wei
Summary: Boron neutron capture therapy (BNCT) is a promising cancer treatment method with good targeting and high efficacy. Measuring B-10 concentrations is vital for treatment effectiveness, but current technology needs improvement.
MOLECULAR PHARMACEUTICS
(2022)
Review
Oncology
Dmitry O. Zharkov, Anna Yudkina, Tim Riesebeck, Polina S. Loshchenova, Evgeny A. Mostovich, Grigory L. Dianov
Summary: Despite progress in cancer therapy, the delivery and accumulation of boron in cancer cells remain major obstacles for the clinical use of BNCT. Incorporating boron-containing nucleotides into the DNA of cancer cells may significantly increase the efficacy of BNCT.
AMERICAN JOURNAL OF CANCER RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Darya S. S. Novopashina, Maya A. A. Dymova, Anna S. S. Davydova, Mariya I. I. Meschaninova, Daria O. O. Malysheva, Elena V. V. Kuligina, Vladimir A. A. Richter, Iaroslav A. A. Kolesnikov, Sergey Yu. Taskaev, Mariya A. A. Vorobyeva
Summary: Boron neutron capture therapy (BNCT) is a unique anti-cancer treatment strategy that improves treatment accuracy by precisely positioning a neutron beam and delivering boron compounds. This study demonstrates the feasibility of using cell-specific RNA aptamers for targeted delivery of boron clusters in BNCT. The results show that the amount of boron-loaded aptamer inside the cell exceeds 1 x 10^9 atoms/cell, and the efficacy of boron-loaded RNA conjugates is comparable to that of B-10-boronophenylalanine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Oncology
Timothy D. Malouff, Danushka S. Seneviratne, Daniel K. Ebner, William C. Stross, Mark R. Waddle, Daniel M. Trifiletti, Sunil Krishnan
Summary: Boron neutron capture therapy (BNCT) is an emerging treatment modality that utilizes boron-10 to target tumors and has shown promising results in various cancer types in clinical studies.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, Research & Experimental
Satoshi Okada, Kai Nishimura, Qarri Ainaya, Kouichi Shiraishi, Sergey A. Anufriev, Igor B. Sivaev, Yoshinori Sakurai, Minoru Suzuki, Masayuki Yokoyama, Hiroyuki Nakamura
Summary: In this study, a gadolinium-boron-conjugated albumin (Gd-MID-BSA) was developed for MRI-guided neutron capture therapy. The accumulation of Gd-MID-BSA in tumors was confirmed by MRI and biodistribution analysis. The concentration ratios of boron and gadolinium in tumors satisfied the requirements for boron neutron capture therapy (BNCT) and gadolinium neutron capture therapy (GdNCT). The conjugation of gadolinium and boron in the albumin molecule enhanced the therapeutic effect of BNCT and showed potential as a promising treatment for malignant tumors.
MOLECULAR PHARMACEUTICS
(2023)
Article
Chemistry, Multidisciplinary
David Kodr, Cansu Pinar Yenice, Anna Simonova, Dijana Pavlovic Saftic, Radek Pohl, Veronika Sykorova, Mayreli Ortiz, Ludek Havran, Miroslav Fojta, Zbigniew J. Lesnikowski, Ciara K. O'Sullivan, Michal Hocek
Summary: A series of modified nucleoside triphosphates bearing dicarba-nido-undecaborate or metal bis(dicarbollide) groups were prepared and utilized for DNA synthesis and redox labeling. The combination of these redox labels allowed for the first fully orthogonal redox coding of all four canonical nucleobases, enabling determination of nucleobase composition of short DNA stretches with electrochemical readout in one simple primer extension experiment.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Yuquan Wang, Giacomo Reina, Heon Gyu Kang, Xiaoxiao Chen, Yajuan Zou, Yoshie Ishikawa, Minoru Suzuki, Naoki Komatsu
Summary: Boron neutron capture therapy (BNCT) is a non-invasive cancer treatment that utilizes nuclear fission of B-10 upon neutron irradiation. In this study, B-10 enriched boron carbide nanoparticle is functionalized with polyglycerol to improve its dispersibility in a physiological environment. Pharmacokinetic experiments show that this modified nanoparticle fulfills the requirements for BNCT and in vivo study reveals its significant effect in suppressing cancer growth and eradicating cancer with the help of near-infrared light irradiation.
Review
Oncology
Xiang Cheng, Fanfan Li, Lizhen Liang
Summary: Boron neutron capture therapy (BNCT) is an effective binary modality for treating malignancies. It has been used in various cancer types, but there are still challenges that need to be addressed through further research and improvement.
Article
Oncology
Annette G. Beck-Sickinger, Daniel P. Becker, Oksana Chepurna, Bhaskar Das, Sebastian Flieger, Evamarie Hey-Hawkins, Narayan Hosmane, Satish S. Jalisatgi, Hiroyuki Nakamura, Rameshwar Patil, Maria da Graca H. Vicente, Clara Vinas
Summary: This article summarizes current research on the development of boron delivery drugs for boron neutron capture therapy, which were presented and discussed at the National Cancer Institute (NCI) Workshop on Neutron Capture Therapy held on April 20-22, 2022. The most commonly used boron sources are icosahedral boron clusters attached to various molecules such as peptides, proteins, porphyrin derivatives, dendrimers, polymers, and nanoparticles, as well as encapsulated into liposomes. These boron clusters and/or carriers can be labeled with contrast agents, allowing for imaging techniques like PET, SPECT, and fluorescence to quantify tumor-localized boron and serve as theranostic agents.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
(2023)
Article
Chemistry, Medicinal
Liridona Useini, Marija Mojic, Markus Laube, Peter Loennecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Jens Pietzsch, Evamarie Hey-Hawkins
Summary: Fenoprofen is a common NSAID used to treat rheumatoid arthritis, degenerative joint disease, ankylosing spondylitis, and gout. It inhibits the synthesis of prostaglandins by blocking both COX-1 and COX-2 isoforms. Modifications using carborane clusters showed stronger antitumor potential compared to aryl-based compounds.
Article
Pharmacology & Pharmacy
Sebastian Braun, Svetlana Paskas, Markus Laube, Sven George, Bettina Hofmann, Peter Loennecke, Dieter Steinhilber, Jens Pietzsch, Sanja S. Mijatovic, Danijela Maksimovic-Ivanic, Evamarie Hey-Hawkins
Summary: In this study, carborane-containing dual COX-2/5-LO inhibitors were designed by incorporating metabolically stable, sterically demanding, and hydrophobic carboranes into existing inhibitors. Five carborane-containing derivatives showed high inhibitory activities towards COX-2 and 5-LO, with meta-carborane derivative 3 demonstrating higher anticancer activity compared to RWJ-63556. The accumulation of lipid droplets in cells indicated the blockage of COX-2 and 5-LO pathways, suggesting a promising approach for the design of potent dual COX-2/5-LO inhibitors.
ADVANCED THERAPEUTICS
(2023)
Article
Chemistry, Multidisciplinary
Kyzgaldak Ramazanova, Peter Loennecke, Evamarie Hey-Hawkins
Summary: The reactive P-N bond in a racemic mixture of endo-1-phospha-2-azanorbornene (PAN) is cleaved with enantiomerically pure lithium alkoxides and protonation to produce diastereomeric mixtures of P-chiral 1-alkoxy-2,3-dihydrophosphole derivatives. The isolation of these compounds is challenging due to the reversibility of the reaction, but methylation and sulfur protection prevent elimination reaction. The resulting P-chiral diastereomeric 1-alkoxy-2,3-dihydrophosphole sulfide mixtures can be easily separated and characterized, and can be reduced to phosphorus(III) P-stereogenic 1-alkoxy-2,3-dihydrophospholes for use in asymmetric homogeneous transition metal catalysis.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Medicinal
Sebastian Braun, Svetlana Paskas, Markus Laube, Sven George, Bettina Hofmann, Peter Loennecke, Dieter Steinhilber, Jens Pietzsch, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Evamarie Hey-Hawkins
Summary: The presence of inflammatory mediators in the tumor microenvironment indicates cancer-related inflammatory processes, and targeting these mediators and related signal pathways may provide a rational strategy for cancer treatment. This study focuses on incorporating carboranes into dual COX-2/5-LO inhibitors, key enzymes in eicosanoid biosynthesis. The results show that carborane-based tebufelone analogs exhibit no COX inhibition but 5-LO inhibitory activity, and structural modifications enhance their anticancer activity. Thus, this strategy is promising for designing potent 5-LO inhibitors with potential application as cytostatic agents.
Article
Chemistry, Medicinal
Philipp Stockmann, Lydia Kuhnert, Lisa Zoerner, Walther Honscha, Evamarie Hey-Hawkins
Summary: The role of ATP-binding cassette (ABC) transporter-mediated multidrug resistance (MDR) in anti-cancer therapy is challenging, as cancer cells exploit efflux transporters like BCRP to secrete chemotherapeutic substances. In this study, a hybrid BCRP inhibitor was designed by combining a prominent scaffold N-phenylquinazolin-4-amine with a boron-carbon cluster. The resulting compound showed increased inhibitory activity towards human ABCG2 and the ability to reverse drug resistance.
Article
Polymer Science
Gizem Kahraman, Burcu Durcak, Nergis Arsu, Evamarie Hey-Hawkins, Tarik Eren
Summary: Random copolymers containing anthracene and carborane units were synthesized via ring-opening metathesis polymerization. They exhibited various emission behaviors and mechano-chromic properties in solution and as solids. The photodimerization and photocleavage of anthracene groups in the copolymers were investigated by UV-vis spectroscopy at 350 and 254 nm, respectively. The thermal properties of the copolymers were examined from 25 to 600 degrees C under nitrogen and in air.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Inorganic & Nuclear
Meghamala Sarkar, Evamarie Hey-Hawkins, Ramamoorthy Boomishankar
Summary: The encapsulation of icosahedral closo-dicarbadodecaborane (o-, m-, and p-carboranes) as guest molecules in the three isostructural tetrahedral cages [{Pd3(NiPr3)PO}4(Cl-AN)6] (1), [{Pd3(NiPr)3PO}4(Br-AN)6] (2), and [{Pd3(NiPr)3PO}4(H-AN)6] (3) was investigated. The formation of definite host-guest assemblies was confirmed by mass spectrometry, IR, and NMR spectroscopy. Diffusion coefficient measurements and hydrodynamic radius calculations suggested that the carborane isomers were encapsulated inside the cage assemblies. Energy optimization studies indicated that o-Cb was preferentially bound as a guest inside the cages. The stabilization of the carborane guests was attributed to various nonclassical C-HmiddotmiddotmiddotX-type interactions.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Saral Baweja, Aleksandr Kazimir, Peter Loennecke, Evamarie Hey-Hawkins
Summary: Phosphino hydrazones are a versatile class of nitrogen-containing phosphine ligands. In this study, a modular synthesis of phosphino hydrazone ligands was achieved by condensation reactions of three different aryl hydrazines with 3-(diphenylphosphino)propanal (PCHO). The complexation reactions of these ligands with palladium(II) and platinum(II) were investigated, and the catalytic activity of the palladium(II) complexes was explored in a Cu-free Sonogashira cross-coupling reaction, achieving yields up to 96%. It was also shown that the catalytically active species is homogeneous.
Article
Pharmacology & Pharmacy
Aleksandr Kazimir, Benedikt Schwarze, Peter Loennecke, Sanja Jelaca, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Evamarie Hey-Hawkins
Summary: A new complex with potential anti-cancer properties was studied in this research. The complex showed high selectivity towards triple-negative breast cancer cells and no significant effect on other cells. This finding may provide new insights for the treatment of breast cancer.
Article
Chemistry, Inorganic & Nuclear
Zeno B. G. Fickenscher, Peter Loennecke, Anna K. Mueller, Wolfgang Baumann, Barbara Kirchner, Evamarie Hey-Hawkins
Summary: The catalytic activity of heterobimetallic complexes [M-0;Ir-III] (M = Cr, Mo, W) in homogeneous CO2 hydrogenation was studied. [Mo-0;Ir-III] showed the highest activity and an increase in reactivity compared to its monometallic counterparts. The homogeneous nature of the reaction was confirmed and the mechanism was explained by Pauli repulsion lowering the transition state of hydride transfer to CO2.
INORGANIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Kyzgaldak Ramazanova, Soumyadeep Chakrabortty, Fabian Kallmeier, Nadja Kretzschmar, Sergey Tin, Peter Loennecke, Johannes G. de Vries, Evamarie Hey-Hawkins
Summary: Sulfur-protected enantiopure P-chiral 1-phosphanorbornane silyl ethers 5a,b were obtained in high yields via reaction with tert-butyldimethylsilyl chloride (TBDMSCl) and triphenylsilyl chloride (TPSCl), and were subsequently purified and characterized. The bulky monodentate enantiopure phosphorus(III) 1-phosphanorbornane silyl ethers 6a,b were obtained by desulfurization with excess Raney nickel, and showed better activity and selectivity as ligands in iridium-catalyzed asymmetric hydrogenation.
Article
Biochemistry & Molecular Biology
Kyzgaldak Ramazanova, Anna Karina Mueller, Peter Loennecke, Oldamur Holloczki, Barbara Kirchner, Evamarie Hey-Hawkins
Summary: The reactive P-N bond can be cleaved by simple alcohols in 1-phospha-2-azanorbornenes, resulting in a racemic mixture of P-chiral 2,3-dihydrophosphole derivatives. The reversibility of the reaction prevents the isolation of the products, but sulfurization of the phosphorus atom can block the reaction and yield structurally characterized compounds.
Article
Chemistry, Multidisciplinary
Elena Gorbachuk, Toni Grell, Khasan Khayarov, Daina Buzyurova, Marat Ziganshin, Timur Mukhametzyanov, Semen Lapuk, Evamarie Hey-Hawkins, Oleg Sinyashin, Dmitry Yakhvarov
Summary: In the presence of [Mo(CO)(4)(cod)], the reaction of cyclopentaphosphine cyclo-(P5Ph5) with ketones (acetone and cyclooctanone) led to the formation of air-stable trinuclear complexes. These complexes contain bis-phosphanido ligands (PPh-PPh-PPh-PPh-CMe2O-PPh)(2-) and (PPh-PPh-PPh-PPh-C(CH2)(7)O-PPh)(2-) bridging a Mo(CO)(3)-Mo(CO)(3) unit. This reaction expands the substrate scope of 1 with transition metal carbonyl complexes and represents the first examples of carbonyl compound insertion into the P-P bond of cyclic oligophosphorus compounds. The structures of complexes 2 and 3 have been characterized by P-31 NMR and single crystal X-ray diffraction. Furthermore, the thermal properties of the complexes have been studied using differential scanning calorimetry (DSC) and fast scanning calorimetry (FSC).
Article
Chemistry, Inorganic & Nuclear
Saral Baweja, Tom Gabler, Peter Loennecke, Evamarie Hey-Hawkins
Summary: Transition metal coordination chemistry and catalysis often employ phosphine ligands, among which phosphine aldehydes are relatively understudied. In this study, we synthesized 3-(diphenylphosphino)propanal (PCHO) and investigated its complexation behavior with Pd(II) and Pt(II). The catalytic activity of the Pd(II) phosphine aldehyde complexes was examined in Cu-free Sonogashira and Suzuki-Miyaura cross-coupling reactions, confirming the homogeneous nature of the catalytically active species.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Masoume Malmir, Majid M. Heravi, Zahra Yekke-Ghasemi, Masoud Mirzaei
Summary: In this study, a tri-component composite consisting of Fe3O4 nanoparticles, Keggin-type polyoxometalate, and graphene oxide was prepared and investigated as a catalyst for the oxidation of sulfides to sulfoxides. The catalyst showed excellent stability, high yields, and recyclability, making it a promising choice for organic-inorganic hybrid catalytic reactions conducted under mild conditions.
Article
Chemistry, Inorganic & Nuclear
Samuel D. Juarez-Escamilla, Sriloy Dey, Bruno Donnadieu, T. Keith Hollis
Summary: In this study, a bidentate Mo complex was synthesized using metalation and transmetalation methodology. The synthesis was optimized to achieve a high yield. The crystal structure of the bidentate complex was determined. Additionally, alternative forms of ligands were discovered in the reaction.
Article
Chemistry, Inorganic & Nuclear
Mohamed H. Abdel-Rhman, Ghada Samir, Mostafa A. Hussien, Nasser M. Hosny
Summary: This study investigated the dissolution performance of hydrazine carbonate solution on zirconium dibutyl phosphate (Zr-DBP), and found that hydrazine carbonate solution could promote the dissolution of Zr-DBP. The effects of dissolution temperature and hydrogen peroxide concentration on the dissolution efficiency were also explored, and the corrosion effect on stainless steel by hydrazine carbonate solution was studied.
Article
Chemistry, Inorganic & Nuclear
Qiaofang Fu, Fangyu Tan, Wu Ying
Summary: This study successfully prepared vermiculite/g-C3N4/TiO2 composites and found that under specific conditions, the composites exhibited excellent degradation effects, with a high degradation rate for methylene blue. Additionally, the composites were able to enhance surface area, reduce carrier loading rate, improve light energy utilization, and enhance durability.
Article
Chemistry, Inorganic & Nuclear
Annabelle G. W. Hodson, Robert T. Mason
Summary: Functionalised polystyrene resins have been found to be efficient catalysts in the synthesis of specific complexes, with the conversion rate controlled by the polymer structure. The addition of amines or amino acids can further yield substituted 13-butadienyl complexes, which have been analyzed by NMR.
Article
Chemistry, Inorganic & Nuclear
C. Kavitha, S. Anbarasan, P. Subramaniam
Summary: The sulfoxidation of PMAAs by the oxo(salen)chromium(V) complex in aqueous acetonitrile medium was studied. The rate of the reaction is influenced by the polarity of the medium and the substituents on PMAA, with electron donating substituents accelerating the reaction and electron withdrawing substituents retarding the reaction.
Article
Chemistry, Inorganic & Nuclear
Qiang-Qiang Liu, Mithun Kumar Ghosh, Shu-Lan Cai, Xiao-Hong Liu, Lu Lu, Mohd. Muddassir, Tanmay Kumar Ghorai, Jun Wang
Summary: Three newly developed coordination polymers (CPs) with semiconducting properties were synthesized using hydrothermal methods. These CPs exhibit superior photocatalytic activity and can degrade organic pollutants effectively.
Article
Chemistry, Inorganic & Nuclear
Mehrnaz Aliahmadi, Ali Nemati Kharat, Jan Janczak
Summary: This study proposes a method for synthesizing allyl alcohol using cost-effective and renewable bio-resource glycerol. By utilizing catalysts, alcohol as a solvent, and a reducing agent, allyl alcohol with an efficiency of 100% was obtained. The structures of the newly synthesized complexes were determined using X-ray single crystallography.
Article
Chemistry, Inorganic & Nuclear
Ji-Yan Gao, Nan Zhang, Dong-Sheng Huang, Xiang-Rong Liu, Zai-Wen Yang, Shun-Sheng Zhao
Summary: Two new transition metal complexes I and II were synthesized and characterized. The complexes exhibited strong thermal stabilities and showed effective binding to CT-DNA and BSA. Complex II exhibited stronger inhibition activity against P. aeruginosa than gentamicin sulfate. These complexes have potential applications in drug research.
Article
Chemistry, Inorganic & Nuclear
Rishabh Ujjval, Hilal Ahmad Khan, Chinnappan Sivasankar, Natesan Thirupathi
Summary: In this study, a rigid 2-aminobenzimidazole type guanidine and its platinum complexes were synthesized through a series of reactions and characterized by various physical and chemical methods. The reaction mechanism was also explained through DFT calculations.
Article
Chemistry, Inorganic & Nuclear
Marcelo Carpes Nunes, Thais Zaboenco, Vinicius Kemper Melara, Gabriel Barros Baptistella, Andre Luiz Barboza Formiga, Andersson Barison, Fabio Souza Nunes
Summary: A new luminescent molecular thermometer has been developed, which uses the spin-crossover equilibrium of a nickelcyclen derivative to measure temperature. The sensor shows high sensitivity and accuracy.
Article
Chemistry, Inorganic & Nuclear
Yuyu Shan, Zhenqin Zhao, Xia Zhang, Zhan Wu, Xiu-Ling Li
Summary: In this study, a new bridging ligand was synthesized through refluxing, and two mononuclear Cu(I) complexes and two trinuclear Cu(I)-Eu(III) complexes were obtained through self-assembly. The Cu(I) antenna chromophores successfully transferred energy to the Eu(III) centers, achieving sensitized Eu(III) luminescence.
Article
Chemistry, Inorganic & Nuclear
Gabriela Sanchez-Lecuona, Mayra C. Vazquez-Nunez, Bruno Donnadieu, Miguel A. Munoz-Hernandez, Virginia Montiel-Palma
Summary: The reaction of RuHCl(PPh3)3 with GaMe3 has been studied and the obtained complexes were analyzed in detail. The results indicate the formation of a Ru-Ga bond, suggesting the generation of an in situ formed ambiphilic phosphinogallyl ligand. This is of significance for understanding the interaction between metal-halogen bonds and metal-small molecule bonds.
Article
Chemistry, Inorganic & Nuclear
Sevil Sener, Nursel Acar, Fatih Dumludag
Summary: The synthesis, characterization, spectroscopic and bonding features of a new Co (II) phthalocyanine compound containing two thiocarbohydrazone groups were explained. The compound showed semiconductor properties and potential as a temperature sensor.
Article
Chemistry, Inorganic & Nuclear
Ledja B. O. Davi, Aryanna S. P. N. Costa, Mariana S. Silva, Adriana S. Ribeiro, Cintya D. A. E. S. Barbosa, Julio C. S. Da Silva, Dimas J. P. Lima, Daniela S. Anunciacao
Summary: In this study, a dansyl derivative sensor called o-PDDS was prepared and used for the detection of Al3+ ions in water. The o-PDDS sensor exhibited high sensitivity and linear response towards Al3+ ions. Experimental and computational studies confirmed a 1:1 stoichiometry ratio between o-PDDS and Al3+ ions. Real sample analysis demonstrated the selectivity and detection performance of the sensor, indicating its potential for field use.
