Chromosome 19 miRNA cluster and CEBPB expression specifically mark and potentially drive triple negative breast cancers

Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer

(2018) Wei Li et al.   Cell Metabolism

Enhancer transcription reveals subtype-specific gene expression programs controlling breast cancer pathogenesis

(2017) Hector L. Franco et al.   GENOME RESEARCH

Molecular genetics and cellular events of K-Ras-driven tumorigenesis

(2017) G G Jinesh et al.   ONCOGENE

Surface PD-L1, E-cadherin, CD24, and VEGFR2 as markers of epithelial cancer stem cells associated with rapid tumorigenesis

(2017) Goodwin G. Jinesh et al.   Scientific Reports

Pim kinase isoforms: devils defending cancer cells from therapeutic and immune attacks

(2016) Goodwin G. Jinesh et al.   APOPTOSIS

Blebbishields and mitotic cells exhibit robust macropinocytosis

(2016) Goodwin G. Jinesh et al.   BIOFACTORS

Blebbishield emergency program: an apoptotic route to cellular transformation

(2016) G G Jinesh et al.   CELL DEATH AND DIFFERENTIATION

RAD51 Mediates Resistance of Cancer Stem Cells to PARP Inhibition in Triple-Negative Breast Cancer

(2016) Yajing Liu et al.   CLINICAL CANCER RESEARCH

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

(2016) Giampaolo Bianchini et al.   Nature Reviews Clinical Oncology

Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts

(2016) Donghong Zhang et al.   NUCLEIC ACIDS RESEARCH

Novel PKC-ζ to p47phox interaction is necessary for transformation from blebbishields

(2016) Goodwin G. Jinesh et al.   Scientific Reports

Smac mimetic with TNF-  targets Pim-1 isoforms and reactive oxygen species production to abrogate transformation from blebbishields

(2015) G. G. Jinesh et al.   BIOCHEMICAL JOURNAL

MicroRNA-520g Confers Drug Resistance by Regulating p21 Expression in Colorectal Cancer

(2015) Yang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predicting response and survival in chemotherapy-treated triple-negative breast cancer

(2014) A Prat et al.   BRITISH JOURNAL OF CANCER

MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumour-suppressor genes in ER+ breast cancer

(2014) Aoife Ward et al.   JOURNAL OF PATHOLOGY

The Oncogenic STP Axis Promotes Triple-Negative Breast Cancer via Degradation of the REST Tumor Suppressor

(2014) Kristen L. Karlin et al.   Cell Reports

Bladder Cancer Stem Cells: Biological and Therapeutic Perspectives

(2014) Goodwin G. et al.   Current Stem Cell Research & Therapy

Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries

(2013) J. S. Jakobsen et al.   GENOME RESEARCH

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR

(2013) Claudia L Kleinman et al.   NATURE GENETICS

Genomic Insights into Triple-Negative and HER2-Positive Breast Cancers Using Isogenic Model Systems

(2013) Prakriti Mudvari et al.   PLoS One

CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer

(2013) S. Loi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

(2013) J. Zuin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blebbishields, the emergency program for cancer stem cells: sphere formation and tumorigenesis after apoptosis

(2012) G G Jinesh et al.   CELL DEATH AND DIFFERENTIATION

The microRNA cluster C19MC is deregulated in parathyroid tumours

(2012) Valentina Vaira et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

In hepatocellular carcinoma miR-519d is up-regulated by p53 and DNA hypomethylation and targets CDKN1A/p21, PTEN, AKT3 and TIMP2

(2012) Francesca Fornari et al.   JOURNAL OF PATHOLOGY

MicroRNA profiling of hepatocarcinogenesis identifies C19MC cluster as a novel prognostic biomarker in hepatocellular carcinoma

(2012) Claudia Augello et al.   LIVER INTERNATIONAL

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Regulatory evolution through divergence of a phosphoswitch in the transcription factor CEBPB

(2011) Vincent J. Lynch et al.   NATURE

The Two Stem Cell MicroRNA Gene Clusters C19MC and miR-371-3 Are Activated by Specific Chromosomal Rearrangements in a Subgroup of Thyroid Adenomas

(2010) Volkhard Rippe et al.   PLoS One

The Transcription Factor REST Is Lost in Aggressive Breast Cancer

(2010) Matthew P. Wagoner et al.   PLoS Genetics

C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts

(2009) M.-L. Bortolin-Cavaille et al.   NUCLEIC ACIDS RESEARCH

Profiling RE1/REST-mediated histone modifications in the human genome

(2009) Deyou Zheng et al.   GENOME BIOLOGY

Race and triple negative threats to breast cancer survival: a population-based study in Atlanta, GA

(2008) Mary Jo Lund et al.   BREAST CANCER RESEARCH AND TREATMENT

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

Critical Role for Transcription Factor C/EBP-  in Regulating the Expression of Death-Associated Protein Kinase 1

(2008) P. Gade et al.   MOLECULAR AND CELLULAR BIOLOGY