Ethanol and unsaturated dietary fat induce unique patterns of hepatic ω-6 and ω-3 PUFA oxylipins in a mouse model of alcoholic liver disease

Mammalian Sirtuin 1 Is Involved in the Protective Action of Dietary Saturated Fat against Alcoholic Fatty Liver in Mice

(2018) Min You et al.   JOURNAL OF NUTRITION

Ablation of cytochrome P450 omega-hydroxylase 4A14 gene attenuates hepatic steatosis and fibrosis

(2017) Xiaoyan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice

(2017) Wenliang Zhang et al.   Scientific Reports

CYP2J2 and Its Metabolites EETs Attenuate Insulin Resistance via Regulating Macrophage Polarization in Adipose Tissue

(2017) Meiyan Dai et al.   Scientific Reports

Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice

(2017) Poonamjot Deol et al.   Scientific Reports

Saturated and Unsaturated Dietary Fats Differentially Modulate Ethanol-Induced Changes in Gut Microbiome and Metabolome in a Mouse Model of Alcoholic Liver Disease

(2016) Irina A. Kirpich et al.   AMERICAN JOURNAL OF PATHOLOGY

Pro-resolving mediators produced from EPA and DHA: Overview of the pathways involved and their mechanisms in metabolic syndrome and related liver diseases

(2016) Cristina López-Vicario et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lipidomic analysis of patients with microbial invasion of the amniotic cavity reveals up-regulation of leukotriene B4

(2016) Krishna Rao Maddipati et al.   FASEB JOURNAL

Clinical chorioamnionitis at term: the amniotic fluid fatty acyl lipidome

(2016) Krishna Rao Maddipati et al.   JOURNAL OF LIPID RESEARCH

Alcohol produces distinct hepatic lipidome and eicosanoid signature in lean and obese

(2016) Puneet Puri et al.   JOURNAL OF LIPID RESEARCH

CYP450-derived oxylipins mediate inflammatory resolution

(2016) Derek W. Gilroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

15-Lipoxygenase metabolites of α-linolenic acid, [13-(S)-HPOTrE and 13-(S)-HOTrE], mediate anti-inflammatory effects by inactivating NLRP3 inflammasome

(2016) Naresh Kumar et al.   Scientific Reports

CYP2J2 overexpression attenuates nonalcoholic fatty liver disease induced by high-fat diet in mice

(2015) Guangzhi Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways

(2015) Nathaniel W. Snyder et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effects of Dietary Different Doses of Copper and High Fructose Feeding on Rat Fecal Metabolome

(2015) Xiaoli Wei et al.   JOURNAL OF PROTEOME RESEARCH

Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice

(2015) Todd R. Harris et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

LRH-1 mediates anti-inflammatory and antifungal phenotype of IL-13-activated macrophages through the PPARγ ligand synthesis

(2015) Lise Lefèvre et al.   Nature Communications

Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs

(2015) Melissa Gabbs et al.   Advances in Nutrition

Eicosanomic profiling reveals dominance of the epoxygenase pathway in human amniotic fluid at term in spontaneous labor

(2014) Krishna Rao Maddipati et al.   FASEB JOURNAL

Inhibition of heat shock protein 90 alleviates steatosis and macrophage activation in murine alcoholic liver injury

(2014) Aditya Ambade et al.   JOURNAL OF HEPATOLOGY

Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis

(2014) Rohit Loomba et al.   JOURNAL OF LIPID RESEARCH

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Reduced Dietary Omega-6 to Omega-3 Fatty Acid Ratio and 12/15-Lipoxygenase Deficiency Are Protective against Chronic High Fat Diet-Induced Steatohepatitis

(2014) Milos Lazic et al.   PLoS One

Phospholipase A2 regulates eicosanoid class switching during inflammasome activation

(2014) P. C. Norris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

(2014) Cristina López-Vicario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binge Ethanol-Induced HDAC3 Down-RegulatesCpt1αExpression Leading to Hepatic Steatosis and Injury

(2013) Irina Kirpich et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Dietary fat sources differentially modulate intestinal barrier and hepatic inflammation in alcohol-induced liver injury in rats

(2013) Wei Zhong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Soluble Epoxide Hydrolase Deficiency or Inhibition Attenuates Diet-induced Endoplasmic Reticulum Stress in Liver and Adipose Tissue

(2013) Ahmed Bettaieb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Thromboxane Inhibitors Attenuate Inflammatory and Fibrotic Changes in Rat Liver Despite Continued Ethanol Administrations

(2012) Amin A. Nanji et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Preservation of Hepatocyte Nuclear Factor-4α Contributes to the Beneficial Effect of Dietary Medium Chain Triglyceride on Alcohol-Induced Hepatic Lipid Dyshomeostasis in Rats

(2012) Qiong Li et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Binge Alcohol-Induced Microvesicular Liver Steatosis and Injury are Associated with Down-Regulation of Hepatic Hdac1, 7, 9, 10, 11 and Up-Regulation of Hdac3

(2012) Irina Kirpich et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health

(2012) Christophe Morisseau et al.   Annual Review of Pharmacology and Toxicology

Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: New evidence on the potential therapeutic mechanism

(2012) Claudia O. Zein et al.   HEPATOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Inhibition of Soluble Epoxide Hydrolase Attenuates High-Fat-Diet–Induced Hepatic Steatosis by Reduced Systemic Inflammatory Status in Mice

(2012) Yan Liu et al.   PLoS One

Lipidic last breath of life in patients with alcoholic liver disease

(2012) Joanna Raszeja-Wyszomirska et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The Type of Dietary Fat Modulates Intestinal Tight Junction Integrity, Gut Permeability, and Hepatic Toll-Like Receptor Expression in a Mouse Model of Alcoholic Liver Disease

(2011) Irina A. Kirpich et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century

(2011) Tanya L Blasbalg et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Stability and analysis of eicosanoids and docosanoids in tissue culture media

(2011) Krishna Rao Maddipati et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Lipoxins: regulators of resolution

(2010) Aidan Ryan et al.   CURRENT OPINION IN PHARMACOLOGY

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

(2010) Sung Hwan Ki et al.   HEPATOLOGY

Chronic Alcohol Exposure Increases Circulating Bioactive Oxidized Phospholipids

(2010) Lili Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2010) Ariel E. Feldstein et al.   JOURNAL OF LIPID RESEARCH

Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

(2010) Irina A. Kirpich et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Treatment of alcoholic liver disease

(2010) Thomas H. Frazier et al.   Therapeutic Advances in Gastroenterology

Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation

(2009) P. Chen et al.   FEBS LETTERS

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

5-lipoxygenase deficiency reduces hepatic inflammation and tumor necrosis factor α-induced hepatocyte damage in hyperlipidemia-prone ApoE-null mice

(2009) Marcos Martínez-Clemente et al.   HEPATOLOGY