Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis

Whole-genome view of the consequences of a population bottleneck using 2926 genome sequences from Finland and United Kingdom

(2017) Himanshu Chheda et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis

(2017) Unnur Styrkarsdottir et al.   NATURE GENETICS

A Whole Exome Study Identifies Novel Candidate Genes for Vertebral Bone Marrow Signal Changes (Modic Changes)

(2017) Minna Kraatari et al.   SPINE

Targeted re-sequencing of linkage region on 2q21 identifies a novel functional variant for hip and knee osteoarthritis

(2016) M. Taipale et al.   OSTEOARTHRITIS AND CARTILAGE

FIP1L1 presence in FIP1L1-RARA or FIP1L1-PDGFRA differentially contributes to the pathogenesis of distinct types of leukemia

(2014) Junko Iwasaki et al.   ANNALS OF HEMATOLOGY

A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism

(2014) Sandra Salem et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31

(2014) Unnur Styrkarsdottir et al.   NATURE GENETICS

Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study

(2014) Yolande F. M. Ramos et al.   PLoS One

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

(2014) Elaine T. Lim et al.   PLoS Genetics

The genetics and functional analysis of primary osteoarthritis susceptibility

(2013) Louise N. Reynard et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Osteoarthritis year 2013 in review: genetics and genomics

(2013) A. Gonzalez   OSTEOARTHRITIS AND CARTILAGE

Defining and mapping the person with osteoarthritis for population studies and public health

(2013) E. Thomas et al.   RHEUMATOLOGY

The Identification of Trans-acting Factors That Regulate the Expression of GDF5 via the Osteoarthritis Susceptibility SNP rs143383

(2013) Catherine M. Syddall et al.   PLoS Genetics

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Theo Vos et al.   LANCET

Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA

(2012) Y. Xu et al.   OSTEOARTHRITIS AND CARTILAGE

dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions

(2011) Xiaoming Liu et al.   HUMAN MUTATION

The functional spectrum of low-frequency coding variation

(2011) Gabor T Marth et al.   GENOME BIOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis

(2010) C. Karlsson et al.   OSTEOARTHRITIS AND CARTILAGE

A genetic marker at the OLIG3/TNFAIP3 locus associates with methotrexate continuation in early inflammatory polyarthritis: results from the Norfolk Arthritis Register

(2010) D Plant et al.   PHARMACOGENOMICS JOURNAL

Wnt signaling and osteoarthritis

(2008) Frank P. Luyten et al.   BONE

3′ end mRNA processing: molecular mechanisms and implications for health and disease

(2008) Sven Danckwardt et al.   EMBO JOURNAL