The threshold of an excitable system serves as a control mechanism for noise filtering during chemotaxis

Insight from the maximal activation of the signal transduction excitable network inDictyostelium discoideum

(2018) Marc Edwards et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement

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Altering the threshold of an excitable signal transduction network changes cell migratory modes

(2017) Yuchuan Miao et al.   NATURE CELL BIOLOGY

Locally excitable Cdc42 signals steer cells during chemotaxis

(2015) Hee Won Yang et al.   NATURE CELL BIOLOGY

Excitable Signal Transduction Induces Both Spontaneous and Directional Cell Asymmetries in the Phosphatidylinositol Lipid Signaling System for Eukaryotic Chemotaxis

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Self-organization of protrusions and polarity during eukaryotic chemotaxis

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Actin and PIP3 waves in giant cells reveal the inherent length scale of an excited state

(2014) Matthias Gerhardt et al.   JOURNAL OF CELL SCIENCE

Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis

(2014) Ming Tang et al.   Nature Communications

An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration

(2013) Chuan-Hsiang Huang et al.   NATURE CELL BIOLOGY

Actin cytoskeleton of chemotactic amoebae operates close to the onset of oscillations

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Excitable behavior in amoeboid chemotaxis

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Interaction of Motility, Directional Sensing, and Polarity Modules Recreates the Behaviors of Chemotaxing Cells

(2013) Changji Shi et al.   PLoS Computational Biology

An Excitable Cortex and Memory Model Successfully Predicts New Pseudopod Dynamics

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Biased excitable networks: how cells direct motion in response to gradients

(2011) Pablo A Iglesias et al.   CURRENT OPINION IN CELL BIOLOGY

Modular systems approach to understanding the interaction of adaptive and monostable and bistable threshold processes

(2011) D. Seaton et al.   IET Systems Biology

Activated Membrane Patches Guide Chemotactic Cell Motility

(2011) Inbal Hecht et al.   PLoS Computational Biology

Transient Localized Patterns in Noise-Driven Reaction-Diffusion Systems

(2010) Inbal Hecht et al.   PHYSICAL REVIEW LETTERS

Cells navigate with a local-excitation, global-inhibition-biased excitable network

(2010) Y. Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling cellular deformations using the level set formalism

(2008) Liu Yang et al.   BMC Systems Biology

Navigating through models of chemotaxis

(2008) Pablo A Iglesias et al.   CURRENT OPINION IN CELL BIOLOGY

Stochastic control of spontaneous signal generation for gradient sensing in chemotaxis

(2008) Honda Naoki et al.   JOURNAL OF THEORETICAL BIOLOGY

Positive feedback sharpens the anaphase switch

(2008) Liam J. Holt et al.   NATURE