Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes

The role of blood and CSF biomarkers in the evaluation of new treatments against multiple sclerosis

(2017) Jan Lycke et al.   Expert Review of Clinical Immunology

Loss of Gas6 and Axl signaling results in extensive axonal damage, motor deficits, prolonged neuroinflammation, and less remyelination following cuprizone exposure

(2017) Alex K. Ray et al.   GLIA

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

(2017) Cheryl E. G. Leyns et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TREM2, Microglia, and Neurodegenerative Diseases

(2017) Felix L. Yeh et al.   TRENDS IN MOLECULAR MEDICINE

The role of interleukin-6 signaling in nervous tissue

(2016) Michelle Rothaug et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

In-Depth Cerebrospinal Fluid Quantitative Proteome and Deglycoproteome Analysis: Presenting a Comprehensive Picture of Pathways and Processes Affected by Multiple Sclerosis

(2016) Ann Cathrine Kroksveen et al.   JOURNAL OF PROTEOME RESEARCH

CSF-PR 2.0: An Interactive Literature Guide to Quantitative Cerebrospinal Fluid Mass Spectrometry Data from Neurodegenerative Disorders

(2016) Astrid Guldbrandsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Change in autoantibody and cytokine responses during the evolution of neuromyelitis optica in patients with systemic lupus erythematosus: A preliminary study

(2016) Katalin T Kovacs et al.   Multiple Sclerosis Journal

Label-free analysis of human cerebrospinal fluid addressing various normalization strategies and revealing protein groups affected by multiple sclerosis

(2016) Jill A. Opsahl et al.   PROTEOMICS

Untangling the brain’s neuroinflammatory and neurodegenerative transcriptional responses

(2016) Karpagam Srinivasan et al.   Nature Communications

Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion

(2016) Peng Jiang et al.   Cell Reports

Change in autoantibody and cytokine responses during the evolution of neuromyelitis optica in patients with systemic lupus erythematosus: A preliminary study

(2016) Katalin T Kovacs et al.   Multiple Sclerosis Journal

TREM2 regulates microglial cell activation in response to demyelination in vivo

(2015) Claudia Cantoni et al.   ACTA NEUROPATHOLOGICA

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

(2015) Yaming Wang et al.   CELL

Emerging role of IL-16 in cytokine-mediated regulation of multiple sclerosis

(2015) Dusanka S. Skundric et al.   CYTOKINE

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

TIMP-1 couples RhoK activation to IL-1β-induced astrocyte responses

(2015) Kasey M. Johnson et al.   NEUROSCIENCE LETTERS

Focal MMP-2 and MMP-9 Activity at the Blood-Brain Barrier Promotes Chemokine-Induced Leukocyte Migration

(2015) Jian Song et al.   Cell Reports

Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study

(2014) Pascal F. Durrenberger et al.   JOURNAL OF NEURAL TRANSMISSION

Diagnostic uncertainty during the transition to secondary progressive multiple sclerosis

(2014) Ilana Katz Sand et al.   Multiple Sclerosis Journal

Modules, networks and systems medicine for understanding disease and aiding diagnosis

(2014) Mika Gustafsson et al.   Genome Medicine

Disease-specific molecular events in cortical multiple sclerosis lesions

(2013) Marie Therese Fischer et al.   BRAIN

Recent progress in omics-driven analysis of MS to unravel pathological mechanisms

(2013) Arjan Malekzadeh et al.   Expert Review of Neurotherapeutics

Tissue Inhibitor of Metalloproteinase 1 Is Preferentially Expressed in Th1 and Th17 T-Helper Cell Subsets and Is a Direct Stat Target Gene

(2013) Adewole Adamson et al.   PLoS One

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice

(2012) May H. Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Discovery and initial verification of differentially abundant proteins between multiple sclerosis patients and controls using iTRAQ and SID-SRM

(2012) Ann C. Kroksveen et al.   Journal of Proteomics

Identification and quantification of differentially expressed proteins in plasma of spinocerebellar ataxia type 12

(2012) Vishnu Swarup et al.   NEUROSCIENCE RESEARCH

Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis

(2011) Jason G Weinger et al.   Journal of Neuroinflammation

Matrix Metalloproteinases and Their Tissue Inhibitors in Cuprizone-Induced Demyelination and Remyelination of Brain White and Gray Matter

(2011) Jelena Škuljec et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Evidence for a two-stage disability progression in multiple sclerosis

(2010) E. Leray et al.   BRAIN

Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death

(2010) S. Veto et al.   BRAIN

Apolipoproteins in the brain: implications for neurological and psychiatric disorders

(2010) David A Elliott et al.   Clinical Lipidology

Contribution of Astrocyte-Derived IL-15 to CD8 T Cell Effector Functions in Multiple Sclerosis

(2010) P. Saikali et al.   JOURNAL OF IMMUNOLOGY

Treatment effects of immunomodulatory therapies at different stages of multiple sclerosis in short-term trials

(2010) D. Bates   NEUROLOGY

The cuprizone animal model: new insights into an old story

(2009) Markus Kipp et al.   ACTA NEUROPATHOLOGICA

Up-Regulation of Soluble Axl and Mer Receptor Tyrosine Kinases Negatively Correlates with Gas6 in Established Multiple Sclerosis Lesions

(2009) Jason G. Weinger et al.   AMERICAN JOURNAL OF PATHOLOGY

Axl−/− mice have delayed recovery and prolonged axonal damage following cuprizone toxicity

(2008) Hannah J. Hoehn et al.   BRAIN RESEARCH

MHC class II exacerbates demyelination in vivo independently of T cells

(2008) Meenaxi M. Hiremath et al.   JOURNAL OF NEUROIMMUNOLOGY

Elevated Matrix Metalloproteinase-9 and Degradation of Perineuronal Nets in Cerebrocortical Multiple Sclerosis Plaques

(2008) Elizabeth Gray et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Gas6 Deficiency Increases Oligodendrocyte Loss and Microglial Activation in Response to Cuprizone-Induced Demyelination

(2008) M. D. Binder et al.   JOURNAL OF NEUROSCIENCE

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Tissue Inhibitors of Metalloproteinases in Cell Signaling: Metalloproteinase-Independent Biological Activities

(2008) W. G. Stetler-Stevenson   Science Signaling