C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid
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Title
C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid
Authors
Keywords
Neutrophils, Rheumatoid arthritis, Macrophages, Synovial fluid, Monocytes, Psoriatic arthritis, T cells, Osteoarthritis
Journal
PLoS One
Volume 12, Issue 12, Pages e0189017
Publisher
Public Library of Science (PLoS)
Online
2017-12-09
DOI
10.1371/journal.pone.0189017
References
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Related references
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- (2012) C. D. Sadik et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of the complement system in rheumatoid arthritis and psoriatic arthritis: Relationship with anti-TNF inhibitors
- (2011) Eleonora Ballanti et al. AUTOIMMUNITY REVIEWS
- Role of C3a Receptors, C5a Receptors, and Complement Protein C6 Deficiency in Collagen Antibody-Induced Arthritis in Mice
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- (2011) H. Subramanian et al. MOLECULAR PHARMACOLOGY
- The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction
- (2010) Claire E. Bamberg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Complement drives Th17 cell differentiation and triggers autoimmune arthritis
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- Role and mechanism of action of complement in regulating T cell immunity
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