Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia

Tamm Horsfall Glycoprotein and Uromodulin: It Is All about the Tubules!

(2015) A. J. Bleyer et al.   Clinical Journal of the American Society of Nephrology

Association between Genotype and Phenotype in Uromodulin-Associated Kidney Disease

(2013) J. L. Moskowitz et al.   Clinical Journal of the American Society of Nephrology

Uromodulin: old friend with new roles in health and disease

(2013) Franca M. Iorember et al.   PEDIATRIC NEPHROLOGY

Uromodulin in Kidney Injury: An Instigator, Bystander, or Protector?

(2012) Tarek M. El-Achkar et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Urinary secretion and extracellular aggregation of mutant uromodulin isoforms

(2012) Céline Schaeffer et al.   KIDNEY INTERNATIONAL

Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies

(2011) Naohiko Anzai et al.   Clinical and Experimental Nephrology

Molecular and Cellular Effects of Tamm-Horsfall Protein Mutations and Their Rescue by Chemical Chaperones

(2011) Lijie Ma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the Bumetanide-sensitive Na+,K+,2Cl−Cotransporter (NKCC2) Is Facilitated by Tamm-Horsfall Protein in a Chloride-sensitive Manner

(2011) Kerim Mutig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The rediscovery of uromodulin (Tamm–Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease

(2011) Luca Rampoldi et al.   KIDNEY INTERNATIONAL

Metabolic Complications Associated With Use of Diuretics

(2011) Biff F. Palmer   SEMINARS IN NEPHROLOGY

Uromodulin concentrations are not associated with incident CKD among persons with coronary artery disease

(2011) Michael G Shlipak et al.   BMC Nephrology

A transgenic mouse model for uromodulin-associated kidney diseases shows specific tubulo-interstitial damage, urinary concentrating defect and renal failure

(2010) Ilenia Bernascone et al.   HUMAN MOLECULAR GENETICS

Tamm-Horsfall Glycoprotein Interacts with Renal Outer Medullary Potassium Channel ROMK2 and Regulates Its Function

(2010) Aparna Renigunta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uromodulin and Chronic Kidney Disease

(2010) Karl Lhotta   KIDNEY & BLOOD PRESSURE RESEARCH

Uromodulin-Associated Kidney Disease

(2010) Anthony J. Bleyer et al.   NEPHRON CLINICAL PRACTICE

Association of Variants at UMOD with Chronic Kidney Disease and Kidney Stones—Role of Age and Comorbid Diseases

(2010) Daniel F. Gudbjartsson et al.   PLoS Genetics

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum

(2009) Siân E. Williams et al.   HUMAN MOLECULAR GENETICS

Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD

(2009) A. Kottgen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multiple loci associated with indices of renal function and chronic kidney disease

(2009) Anna Köttgen et al.   NATURE GENETICS

Production and Characterization of Transgenic Mice Harboring Mutant HumanUMODGene

(2008) Yuichi Takiue et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS