Long-term follow up of human T-cell responses to conserved HIV-1 regions elicited by DNA/simian adenovirus/MVA vaccine regimens

Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects

(2017) Gemma Hancock et al.   Journal of the International AIDS Society

Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines

(2017) Nicola Borthwick et al.   PLoS One

HIV-Host Interactions: Implications for Vaccine Design

(2016) Barton F. Haynes et al.   Cell Host & Microbe

Tissue-specific programming of memory CD8 T cell subsets impacts protection against lethal respiratory virus infection

(2016) Georges Abboud et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection

(2016) Beatrice Ondondo et al.   MOLECULAR THERAPY

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

Control of HIV-1 replication in vitro by vaccine-induced human CD8+ T cells through conserved subdominant Pol epitopes

(2016) Tina Ahmed et al.   VACCINE

Broad HIV-1 inhibition in vitro by vaccine-elicited CD8+ T cells in African adults

(2016) Gaudensia Mutua et al.   Molecular Therapy-Methods & Clinical Development

Clinical Control of HIV-1 by Cytotoxic T Cells Specific for Multiple Conserved Epitopes

(2015) Hayato Murakoshi et al.   JOURNAL OF VIROLOGY

Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV Viremia

(2015) Susan Johnson et al.   JOURNAL OF VIROLOGY

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

(2015) Kai Deng et al.   NATURE

Identification of Effective Subdominant Anti-HIV-1 CD8+ T Cells Within Entire Post-infection and Post-vaccination Immune Responses

(2015) Gemma Hancock et al.   PLoS Pathogens

Conserved immunogens in prime-boost strategies for the next-generation HIV-1 vaccines

(2014) Tomáš Hanke   EXPERT OPINION ON BIOLOGICAL THERAPY

Safety and Tolerability of Conserved Region Vaccines Vectored by Plasmid DNA, Simian Adenovirus and Modified Vaccinia Virus Ankara Administered to Human Immunodeficiency Virus Type 1-Uninfected Adults in a Randomized, Single-Blind Phase I Trial

(2014) Emma-Jo Hayton et al.   PLoS One

Effector-like CD8+ T Cells in the Memory Population Mediate Potent Protective Immunity

(2013) Janelle A. Olson et al.   IMMUNITY

Translating HIV Sequences into Quantitative Fitness Landscapes Predicts Viral Vulnerabilities for Rational Immunogen Design

(2013) Andrew L. Ferguson et al.   IMMUNITY

CD8+T-cell effector function and transcriptional regulation during HIV pathogenesis

(2013) Korey R. Demers et al.   IMMUNOLOGICAL REVIEWS

Vaccine-elicited Human T Cells Recognizing Conserved Protein Regions Inhibit HIV-1

(2013) Nicola Borthwick et al.   MOLECULAR THERAPY

Immune clearance of highly pathogenic SIV infection

(2013) Scott G. Hansen et al.   NATURE

Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine

(2013) Scott M. Hammer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms

(2013) S. G. Hansen et al.   SCIENCE

HIV and HLA Class I: An Evolving Relationship

(2012) Philip J.R. Goulder et al.   IMMUNITY

Optimization and qualification of a multiplex bead array to assess cytokine and chemokine production by vaccine-specific cells

(2012) Olivier D. Defawe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Antiviral Inhibitory Capacity of CD8+ T cells Predicts the Rate of CD4+ T-Cell Decline in HIV-1 Infection

(2012) Hongbing Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Lessons learned from HIV-1 vaccine trials: new priorities and directions

(2012) Andrew J McMichael et al.   NATURE IMMUNOLOGY

HIV-Specific Cytolytic CD4 T Cell Responses During Acute HIV Infection Predict Disease Outcome

(2012) D. Z. Soghoian et al.   Science Translational Medicine

Definition of the viral targets of protective HIV-1-specific T cell responses

(2011) Beatriz Mothe et al.   Journal of Translational Medicine

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Protective Efficacy of Serially Up-Ranked Subdominant CD8+ T Cell Epitopes against Virus Challenges

(2011) Eung-Jun Im et al.   PLoS Pathogens

Perforin Expression Directly Ex Vivo by HIV-Specific CD8+ T-Cells Is a Correlate of HIV Elite Control

(2010) Adam R. Hersperger et al.   PLoS Pathogens

Perforin and IL-2 Upregulation Define Qualitative Differences among Highly Functional Virus-Specific Human CD8+ T Cells

(2010) George Makedonas et al.   PLoS Pathogens

Diversity in T Cell Memory: An Embarrassment of Riches

(2009) Stephen C. Jameson et al.   IMMUNITY

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

(2009) Nilu Goonetilleke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection

(2009) Jesus F. Salazar-Gonzalez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

Vaccines: Correlates of Vaccine‐Induced Immunity

(2008) Stanley A. Plotkin   CLINICAL INFECTIOUS DISEASES

HIV-1 vaccine-induced immunity in the test-of-concept Step Study: a case–cohort analysis

(2008) M Juliana McElrath et al.   LANCET

Broad and Gag-Biased HIV-1 Epitope Repertoires Are Associated with Lower Viral Loads

(2008) Morgane Rolland et al.   PLoS One

Distinct Genetic Loci Control Plasma HIV-RNA and Cellular HIV-DNA Levels in HIV-1 Infection: The ANRS Genome Wide Association 01 Study

(2008) Cyril Dalmasso et al.   PLoS One