Toxicological and bio-distribution profile of a GM-CSF-expressing, double-targeted, chimeric oncolytic adenovirus ONCOS-102 – Support for clinical studies on advanced cancer treatment

Virotherapy overcomes tumor resistance to PD-1-immunotherapy by broad mutanome-directed T cell responses in mice

(2015) N Woller et al.   ZEITSCHRIFT FUR GASTROENTEROLOGIE

Evidence for Oncolytic Virotherapy: Where Have We Got to and Where Are We Going?

(2015) Samantha Turnbull et al.   Viruses-Basel

Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8+T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian cancer

(2015) L Vassilev et al.   OncoImmunology

Oncolytic adenovirus and doxorubicin-based chemotherapy results in synergistic antitumor activity against soft-tissue sarcoma

(2014) Mikko Siurala et al.   INTERNATIONAL JOURNAL OF CANCER

Phase 1 Clinical Trial of Intratumoral Reovirus Infusion for the Treatment of Recurrent Malignant Gliomas in Adults

(2014) Kimberly P Kicielinski et al.   MOLECULAR THERAPY

How To Train Your Oncolytic Virus: the Immunological Sequel

(2014) Richard G Vile   MOLECULAR THERAPY

Local treatment of a pleural mesothelioma tumor with ONCOS-102 induces a systemic antitumor CD8+T-cell response, prominent infiltration of CD8+lymphocytes and Th1 type polarization

(2014) Tuuli Ranki et al.   OncoImmunology

Chemotherapy and Oncolytic Virotherapy: Advanced Tactics in the War against Cancer

(2014) Andrew Nguyen et al.   Frontiers in Oncology

Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients

(2013) Ilkka Liikanen et al.   MOLECULAR THERAPY

Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy

(2012) L. van de Laar et al.   BLOOD

Oncolytic Virus Therapy for Glioblastoma Multiforme

(2012) Guido Wollmann et al.   CANCER JOURNAL

Immune Response Is an Important Aspect of the Antitumor Effect Produced by a CD40L-Encoding Oncolytic Adenovirus

(2012) I. Diaconu et al.   CANCER RESEARCH

Oncolytic viruses in radiation oncology

(2011) Yann Touchefeu et al.   RADIOTHERAPY AND ONCOLOGY

Prolonged systemic circulation of chimeric oncolytic adenovirus Ad5/3-Cox2L-D24 in patients with metastatic and refractory solid tumors

(2010) S Pesonen et al.   GENE THERAPY

Oncolytic Adenoviruses for the Treatment of Human Cancer: Focus on Translational and Clinical Data

(2010) Sari Pesonen et al.   MOLECULAR PHARMACEUTICS

Treatment of Cancer Patients With a Serotype 5/3 Chimeric Oncolytic Adenovirus Expressing GMCSF

(2010) Anniina Koski et al.   MOLECULAR THERAPY

Phase I Clinical Trial of an Adenovirus/Prostate-Specific Antigen Vaccine for Prostate Cancer: Safety and Immunologic Results

(2009) D. M. Lubaroff et al.   CLINICAL CANCER RESEARCH

Systemic adenoviral gene delivery to orthotopic murine breast tumors with ablation of coagulation factors, thrombocytes and Kupffer cells

(2009) Anniina Koski et al.   JOURNAL OF GENE MEDICINE

Current Issues and Future Directions of Oncolytic Adenoviruses

(2009) Masato Yamamoto et al.   MOLECULAR THERAPY

Changing the adenovirus fiber for retaining gene delivery efficacy in the presence of neutralizing antibodies

(2008) M Särkioja et al.   GENE THERAPY