B-cell phenotype and IgD-CD27- memory B cells are affected by TNF-inhibitors and tocilizumab treatment in rheumatoid arthritis

Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients

(2016) Nele Claes et al.   JOURNAL OF IMMUNOLOGY

B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy

(2016) Wilhelmina M. C. Timmermans et al.   PLoS One

Chronic signs of memory B cell activation in patients with Behçet’s disease are partially restored by anti-tumour necrosis factor treatment

(2016) Tim B. van der Houwen et al.   RHEUMATOLOGY

MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis

(2016) Stefano Alivernini et al.   Nature Communications

TNF-α confers resistance to Fas-mediated apoptosis in rheumatoid arthritis through the induction of soluble Fas

(2015) Seokchan Hong et al.   LIFE SCIENCES

Rapid Proliferation and Differentiation of a Subset of Circulating IgM Memory B Cells to a CpG/Cytokine Stimulus In Vitro

(2015) Camilo Vásquez et al.   PLoS One

CD27-IgD- memory B cells are modulated by in vivo interleukin-6 receptor (IL-6R) blockade in rheumatoid arthritis

(2015) Zafar Mahmood et al.   ARTHRITIS RESEARCH & THERAPY

Peripheral blood CD4+CD25+CD127low regulatory T cells are significantly increased by tocilizumab treatment in patients with rheumatoid arthritis: increase in regulatory T cells correlates with clinical response

(2015) Jun Kikuchi et al.   ARTHRITIS RESEARCH & THERAPY

Comparative Effectiveness of Tocilizumab and TNF Inhibitors in Rheumatoid Arthritis Patients: Data from the Rheumatic Diseases Portuguese Register, Reuma.pt

(2015) Vasco C. Romão et al.   Biomed Research International

Restoration of peripheral blood natural killer and B cell levels in patients affected by rheumatoid and psoriatic arthritis during etanercept treatment

(2014) P. Conigliaro et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Human IgE+ B cells are derived from T cell–dependent and T cell–independent pathways

(2014) Magdalena A. Berkowska et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

B Cell Chemoattractant CXCL13 Is Preferentially Expressed by Human Th17 Cell Clones

(2014) R. Takagi et al.   JOURNAL OF IMMUNOLOGY

Deficient TACI Expression on B Lymphocytes of Newborn Mice Leads to Defective Ig Secretion in Response to BAFF or APRIL

(2014) S. Kanswal et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Anti-Tumor Necrosis Factor Therapy in Rheumatoid Arthritis Inhibits Memory B Lymphocytes via Effects on Lymphoid Germinal Centers and Follicular Dendritic Cell Networks

(2014) J. H. Anolik et al.   JOURNAL OF IMMUNOLOGY

IL-6 supports the generation of human long-lived plasma cells in combination with either APRIL or stromal cell-soluble factors

(2014) M Jourdan et al.   LEUKEMIA

Bone resorption correlates with the frequency of CD5+ B cells in the blood of patients with rheumatoid arthritis

(2014) Robby Engelmann et al.   RHEUMATOLOGY

Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels

(2014) Jonathan D Jones et al.   ARTHRITIS RESEARCH & THERAPY

B cell resistance to Fas-mediated apoptosis contributes to their ineffective control by regulatory T cells in rheumatoid arthritis

(2013) Laetitia Rapetti et al.   ANNALS OF THE RHEUMATIC DISEASES

A Distinct Human CD4+ T Cell Subset That Secretes CXCL13 in Rheumatoid Synovium

(2013) Shio Kobayashi et al.   ARTHRITIS AND RHEUMATISM

Interleukin-6 Receptor Blockade Selectively Reduces IL-21 Production by CD4 T Cells and IgG4 Autoantibodies in Rheumatoid Arthritis

(2013) Gustavo Carbone et al.   International Journal of Biological Sciences

The effect of B-cell depletion therapy on serological evidence of B-cell and plasmablast activation in patients with rheumatoid arthritis over multiple cycles of rituximab treatment

(2013) G. Cambridge et al.   JOURNAL OF AUTOIMMUNITY

BAFF and TACI Gene Expression Are Increased in Patients with Untreated Very Early Rheumatoid Arthritis

(2013) R. A. Moura et al.   JOURNAL OF RHEUMATOLOGY

Perigranuloma Localization and Abnormal Maturation of B Cells

(2012) Lieke S. Kamphuis et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Anti-TNF treatment blocks the induction of T cell-dependent humoral responses

(2012) Gabriela Franco Salinas et al.   ANNALS OF THE RHEUMATIC DISEASES

Increased numbers of CD5+ B lymphocytes with a regulatory phenotype in spondylarthritis

(2012) Tineke Cantaert et al.   ARTHRITIS AND RHEUMATISM

To B or Not to B the Conductor of Rheumatoid Arthritis Orchestra

(2012) Rita A. Moura et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Comparative effectiveness and predictors of response to tumour necrosis factor inhibitor therapies in rheumatoid arthritis

(2012) H. Canhao et al.   RHEUMATOLOGY

RF positivity has substantial influence on the peripheral memory B-cell compartment and its modulation by TNF inhibition

(2012) P Roll et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Serum levels of CXCL13 are associated with ultrasonographic synovitis and predict power Doppler persistence in early rheumatoid arthritis treated with non-biological disease-modifying anti-rheumatic drugs

(2012) Serena Bugatti et al.   ARTHRITIS RESEARCH & THERAPY

In vivo effects of the anti-interleukin-6 receptor inhibitor tocilizumab on the B cell compartment

(2011) Petra Roll et al.   ARTHRITIS AND RHEUMATISM

Treatment with TNFα blockers induces phenotypical and functional aberrations in peripheral B cells

(2011) Maria P. Karampetsou et al.   CLINICAL IMMUNOLOGY

Inhibition of MAP kinase in synovium by treatment with tocilizumab in rheumatoid arthritis

(2011) Katsuaki Kanbe et al.   CLINICAL RHEUMATOLOGY

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

(2010) Y.-C. Wu et al.   BLOOD

Alterations on peripheral blood B-cell subpopulations in very early arthritis patients

(2010) R. A. Moura et al.   RHEUMATOLOGY

Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival

(2010) R. A. Moura et al.   RHEUMATOLOGY

B cells from rheumatoid arthritis patients show important alterations on the expression of CD86 and FcgammaRIIb, which are modulated by anti-tumor necrosis factor therapy

(2010) Diego Catalan et al.   ARTHRITIS RESEARCH & THERAPY

Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis

(2010) Rita Cascão et al.   ARTHRITIS RESEARCH & THERAPY

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people

(2009) Giuseppina Colonna-Romano et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor

(2009) M Margarida Souto-Carneiro et al.   ARTHRITIS RESEARCH & THERAPY

Markers of B-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort

(2009) Jacques-Eric Gottenberg et al.   ARTHRITIS RESEARCH & THERAPY

Clinical significance of synovial lymphoid neogenesis and its reversal after anti-tumour necrosis factor   therapy in rheumatoid arthritis

(2008) J D Canete et al.   ANNALS OF THE RHEUMATIC DISEASES

Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint

(2008) Antonio Manzo et al.   ARTHRITIS AND RHEUMATISM

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: Delineation by expression of CD27, IgD, and CD95

(2008) Annett M. Jacobi et al.   ARTHRITIS AND RHEUMATISM

Splenic function and IgM-memory B cells in Crohnʼs disease patients treated with infliximab

(2008) Antonio Di Sabatino et al.   INFLAMMATORY BOWEL DISEASES