CD27-IgD- memory B cells are modulated by in vivo interleukin-6 receptor (IL-6R) blockade in rheumatoid arthritis

Adalimumab in the treatment of rheumatoid arthritis

(2014) Paraskevi V Voulgari et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Increased Frequency of a Unique Spleen Tyrosine Kinase Bright Memory B Cell Population in Systemic Lupus Erythematosus

(2014) Sarah J. Fleischer et al.   Arthritis & Rheumatology

B cells

(2013) Thomas Dörner et al.   CURRENT OPINION IN RHEUMATOLOGY

Interleukin-6 Receptor Blockade Selectively Reduces IL-21 Production by CD4 T Cells and IgG4 Autoantibodies in Rheumatoid Arthritis

(2013) Gustavo Carbone et al.   International Journal of Biological Sciences

Cytokine-producing B cells as regulators of pathogenic and protective immune responses

(2012) Simon Fillatreau   ANNALS OF THE RHEUMATIC DISEASES

Impact of anti-interleukin-6 receptor blockade on circulating T and B cell subsets in patients with systemic lupus erythematosus

(2012) Yuko Shirota et al.   ANNALS OF THE RHEUMATIC DISEASES

B lymphocyte-typing for prediction of clinical response to rituximab

(2012) Hans-Peter Brezinschek et al.   ARTHRITIS RESEARCH & THERAPY

Advances in Human B Cell Phenotypic Profiling

(2012) Denise A. Kaminski et al.   Frontiers in Immunology

Impact of IL-6 receptor inhibition on human memory B cells in vivo: impaired somatic hypermutation in preswitch memory B cells and modulation of mutational targeting in memory B cells

(2011) K. Muhammad et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic Targeting of the Interleukin-6 Receptor

(2011) Toshio Tanaka et al.   Annual Review of Pharmacology and Toxicology

In vivo effects of the anti-interleukin-6 receptor inhibitor tocilizumab on the B cell compartment

(2011) Petra Roll et al.   ARTHRITIS AND RHEUMATISM

B cell immunosenescence: different features of naive and memory B cells in elderly

(2011) Silvio Buffa et al.   BIOGERONTOLOGY

IL-6/IL-6 receptor system and its role in physiological and pathological conditions

(2011) Masahiko Mihara et al.   CLINICAL SCIENCE

B-cell-activating factor receptor expression on naive and memory B cells: relationship with relapse in patients with rheumatoid arthritis following B-cell depletion therapy

(2010) I. de la Torre et al.   ANNALS OF THE RHEUMATIC DISEASES

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

(2010) Daniel Aletaha et al.   ARTHRITIS AND RHEUMATISM

Delayed acquisition of somatic hypermutations in repopulated IGD+CD27+ memory B cell receptors after rituximab treatment

(2009) Khalid Muhammad et al.   ARTHRITIS AND RHEUMATISM

Rapid and sustained improvement in bone and cartilage turnover markers with the anti–interleukin-6 receptor inhibitor tocilizumab plus methotrexate in rheumatoid arthritis patients with an inadequate response to methotrexate: Results from a substudy of the multicenter double-blind, placebo-controlled trial of tocilizumab in inadequate responders to methotrexate alone

(2009) Patrick Garnero et al.   ARTHRITIS AND RHEUMATISM

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people

(2009) Giuseppina Colonna-Romano et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor

(2009) M Margarida Souto-Carneiro et al.   ARTHRITIS RESEARCH & THERAPY

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: Delineation by expression of CD27, IgD, and CD95

(2008) Annett M. Jacobi et al.   ARTHRITIS AND RHEUMATISM

Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease

(2008) N. Nishimoto et al.   BLOOD

Phenotypic and functional heterogeneity of human memory B cells

(2008) Iñaki Sanz et al.   SEMINARS IN IMMUNOLOGY