Broad recruitment of mGBP family members to Chlamydia trachomatis inclusions

Rectal administration of a chlamydial subunit vaccine protects against genital infection and upper reproductive tract pathology in mice

(2017) Roshan Pais et al.   PLoS One

Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense

(2017) Annette Fischer et al.   eLife

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

(2016) Si Ming Man et al.   CELL

Interferon-Inducible GTPases in Host Resistance, Inflammation and Disease

(2016) Danielle Pilla-Moffett et al.   JOURNAL OF MOLECULAR BIOLOGY

Chlamydia cell biology and pathogenesis

(2016) Cherilyn Elwell et al.   NATURE REVIEWS MICROBIOLOGY

Chlamydia trachomatis Is Resistant to Inclusion Ubiquitination and Associated Host Defense in Gamma Interferon-Primed Human Epithelial Cells

(2016) Arun K. Haldar et al.   mBio

Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes

(2016) Elisabeth Kravets et al.   eLife

Interferon-inducible GTPases in cell autonomous and innate immunity

(2015) Etienne Meunier et al.   CELLULAR MICROBIOLOGY

Guanylate Binding Proteins Enable Rapid Activation of Canonical and Noncanonical Inflammasomes in Chlamydia-Infected Macrophages

(2015) Ryan Finethy et al.   INFECTION AND IMMUNITY

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins

(2015) Arun K. Haldar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Translocation of Host Cellular Materials into the Chlamydia trachomatis Inclusion Lumen during Chemical Fixation

(2015) Marcela Kokes et al.   PLoS One

Improved Plaque Assay Identifies a Novel Anti-Chlamydia Ceramide Derivative with Altered Intracellular Localization

(2014) Sebastian Banhart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Triphosphate Induced Dimerization of Human Guanylate Binding Protein 1 Involves Association of the C-Terminal Helices: A Joint Double Electron–Electron Resonance and FRET Study

(2014) Tobias Vöpel et al.   BIOCHEMISTRY

Innate Resistance against Toxoplasma gondii: An Evolutionary Tale of Mice, Cats, and Men

(2014) Ricardo T. Gazzinelli et al.   Cell Host & Microbe

Role of Mouse and Human Autophagy Proteins in IFN- -Induced Cell-Autonomous Responses against Toxoplasma gondii

(2014) J. Ohshima et al.   JOURNAL OF IMMUNOLOGY

The E2-Like Conjugation Enzyme Atg3 Promotes Binding of IRG and Gbp Proteins to Chlamydia- and Toxoplasma-Containing Vacuoles and Host Resistance

(2014) Arun K. Haldar et al.   PLoS One

Chlamydial Intracellular Survival Strategies

(2013) R. J. Bastidas et al.   Cold Spring Harbor Perspectives in Medicine

IRG and GBP Host Resistance Factors Target Aberrant, “Non-self” Vacuoles Characterized by the Missing of “Self” IRGM Proteins

(2013) Arun K. Haldar et al.   PLoS Pathogens

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

(2013) Elizabeth M. Selleck et al.   PLoS Pathogens

IFN-Inducible GTPases in Host Cell Defense

(2012) Bae-Hoon Kim et al.   Cell Host & Microbe

Host HDL biogenesis machinery is recruited to the inclusion ofChlamydia trachomatis-infected cells and regulates chlamydial growth

(2012) John V. Cox et al.   CELLULAR MICROBIOLOGY

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

(2012) Masahiro Yamamoto et al.   IMMUNITY

The GTPase Activity of Murine Guanylate-binding Protein 2 (mGBP2) Controls the Intracellular Localization and Recruitment to the Parasitophorous Vacuole ofToxoplasma gondii

(2012) Elisabeth Kravets et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication

(2012) D. Degrandi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection

(2011) B.-H. Kim et al.   SCIENCE

Development of a Transformation System for Chlamydia trachomatis: Restoration of Glycogen Biosynthesis by Acquisition of a Plasmid Shuttle Vector

(2011) Yibing Wang et al.   PLoS Pathogens

Intracellular Trafficking of Guanylate-Binding Proteins Is Regulated by Heterodimerization in a Hierarchical Manner

(2010) Nathalie Britzen-Laurent et al.   PLoS One

Acquisition of nutrients by Chlamydiae: unique challenges of living in an intracellular compartment

(2009) Hector Alex Saka et al.   CURRENT OPINION IN MICROBIOLOGY

Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ

(2009) Illya Tietzel et al.   PLoS One

Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies

(2008) Alexandra Kresse et al.   BMC GENOMICS