Prominent features of the amino acid mutation landscape in cancer

Cancer cell behaviors mediated by dysregulated pH dynamics at a glance

(2017) Katharine A. White et al.   JOURNAL OF CELL SCIENCE

Exploring preferred amino acid mutations in cancer genes: Applications to identify potential drug targets

(2016) P. Anoosha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity

(2016) Bradley A. Webb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

COSMIC: somatic cancer genetics at high-resolution

(2016) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Microscopic mechanisms that govern the titration response and pK a values of buried residues in staphylococcal nuclease mutants

(2016) Yuqing Zheng et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

(2015) Khalid O Alfarouk et al.   Cancer Cell International

Metabolism and Its Sequelae in Cancer Evolution and Therapy

(2015) Robert J. Gillies et al.   CANCER JOURNAL

Integration of molecular pathology, epidemiology and social science for global precision medicine

(2015) Akihiro Nishi et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Genome-wide mutational spectra analysis reveals significant cancer-specific heterogeneity

(2015) Hua Tan et al.   Scientific Reports

pH sensing by FAK-His58 regulates focal adhesion remodeling

(2013) Chang-Hoon Choi et al.   JOURNAL OF CELL BIOLOGY

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R

(2013) D S Meyer et al.   Oncogenesis

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Structural Reorganization Triggered by Charging of Lys Residues in the Hydrophobic Interior of a Protein

(2012) Michael S. Chimenti et al.   STRUCTURE

Insights into the oncogenic effects of /PIK3CA/ mutations from the structure of p110α/p85α

(2011) Chuan-Hsiang Huang et al.   CELL CYCLE

A flexible R package for nonnegative matrix factorization

(2010) Renaud Gaujoux et al.   BMC BIOINFORMATICS

Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field

(2010) S. Ogino et al.   GUT

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Effects of oncogenic p110α subunit mutations on the lipid kinase activity of phosphoinositide 3-kinase

(2008) Jeffrey D. Carson et al.   BIOCHEMICAL JOURNAL

Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

(2008) Christian Frantz et al.   JOURNAL OF CELL BIOLOGY

Lipid binding domains: more than simple lipid effectors

(2008) Robert V. Stahelin   JOURNAL OF LIPID RESEARCH