Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors

Upregulation of neurotrophins by S 47445, a novel positive allosteric modulator of AMPA receptors in aged rats

(2017) Francesca Calabrese et al.   PHARMACOLOGICAL RESEARCH

Synaptic AMPA receptor composition in development, plasticity and disease

(2016) Jeremy M. Henley et al.   NATURE REVIEWS NEUROSCIENCE

Structure and organization of heteromeric AMPA-type glutamate receptors

(2016) Beatriz Herguedas et al.   SCIENCE

Structure, Dynamics, and Allosteric Potential of Ionotropic Glutamate Receptor N-Terminal Domains

(2015) James Krieger et al.   BIOPHYSICAL JOURNAL

AMPA receptor potentiators: from drug design to cognitive enhancement

(2015) Kathryn M Partin   CURRENT OPINION IN PHARMACOLOGY

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

AMPA receptor positive allosteric modulators: a patent review

(2013) Bernard Pirotte et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Cooperativity of Allosteric Receptors

(2013) Stuart J. Edelstein et al.   JOURNAL OF MOLECULAR BIOLOGY

Form follows function: BDNF and its involvement in sculpting the function and structure of synapses

(2013) Marta Zagrebelsky et al.   NEUROPHARMACOLOGY

Functional Insights from Glutamate Receptor Ion Channel Structures

(2012) Janesh Kumar et al.   Annual Review of Physiology

Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy

(2012) Jonathan E. Harms et al.   NEUROPHARMACOLOGY

Structural and Functional Analysis of Two New Positive Allosteric Modulators of GluA2 Desensitization and Deactivation

(2011) D. E. Timm et al.   MOLECULAR PHARMACOLOGY

Molecular Mechanism of Flop Selectivity and Subsite Recognition for an AMPA Receptor Allosteric Modulator: Structures of GluA2 and GluA3 in Complexes with PEPA

(2010) Ahmed H. Ahmed et al.   BIOCHEMISTRY

Challenges for and current status of research into positive modulators of AMPA receptors

(2010) Simon E Ward et al.   BRITISH JOURNAL OF PHARMACOLOGY

DRUG FOCUS: S 18986: A Positive Allosteric Modulator of AMPA-Type Glutamate Receptors Pharmacological Profile of a Novel Cognitive Enhancer

(2010) Katy Bernard et al.   CNS Neuroscience & Therapeutics

The AMPA receptor as a therapeutic target: current perspectives and emerging possibilities

(2010) Ian R Mellor   Future Medicinal Chemistry

Brief ampakine treatments slow the progression of Huntington's disease phenotypes in R6/2 mice

(2010) Danielle A. Simmons et al.   NEUROBIOLOGY OF DISEASE

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis

(2009) Kim-Da Destot-Wong et al.   NEUROPHARMACOLOGY