Modulation of kanamycin B and kanamycin A biosynthesis in Streptomyces kanamyceticus via metabolic engineering

Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora

(2016) Xianpu Ni et al.   Microbial Cell Factories

Biosynthesis of Epimers C2 and C2a in the Gentamicin C Complex

(2015) Yawen Gu et al.   CHEMBIOCHEM

A rapid and reliable strategy for chromosomal integration of gene(s) with multiple copies

(2015) Pengfei Gu et al.   Scientific Reports

Improvement of gougerotin and nikkomycin production by engineering their biosynthetic gene clusters

(2013) Deyao Du et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The Last Step of Kanamycin Biosynthesis: Unique Deamination Reaction Catalyzed by the α-Ketoglutarate-Dependent Nonheme Iron Dioxygenase KanJ and the NADPH-Dependent Reductase KanK

(2012) Hilda Sucipto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation

(2011) Je Won Park et al.   Nature Chemical Biology

Construction of kanamycin B overproducing strain by genetic engineering of Streptomyces tenebrarius

(2010) Xianpu Ni et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biosynthetic genes for aminoglycoside antibiotics

(2009) Fumitaka Kudo et al.   JOURNAL OF ANTIBIOTICS

Heterologous production of paromamine in Streptomyces lividans TK24 using kanamycin biosynthetic genes from Streptomyces kanamyceticus ATCC12853

(2009) Keshav Kumar Nepal et al.   MOLECULES AND CELLS

Genetic Modulation of the Overexpression of Tailoring Genes eryK and eryG Leading to the Improvement of Erythromycin A Purity and Production in Saccharopolyspora erythraea Fermentation

(2008) Y. Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A motif in the C-terminal domain of ϕC31 integrase controls the directionality of recombination

(2008) Paul A. Rowley et al.   NUCLEIC ACIDS RESEARCH