Creation of an immunodeficient HLA-transgenic mouse (HUMAMICE) and functional validation of human immunity after transfer of HLA-matched human cells

Co-transplantation of human fetal thymus, bone and CD34+ cells into young adult immunodeficient NOD/SCID IL2Rγnull mice optimizes humanized mice that mount adaptive antibody responses

(2015) Yun Shin Chung et al.   CLINICAL IMMUNOLOGY

G-CSF mobilizes CD34 + regulatory monocytes that inhibit graft-versus-host disease

(2015) Maud D’Aveni et al.   Science Translational Medicine

Mild Heat Treatment Primes Human CD34+ Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model

(2015) Maegan L. Capitano et al.   STEM CELLS

Humanized mice: novel model for studying mechanisms of human immune-based therapies

(2013) Louis Gonzalez et al.   IMMUNOLOGIC RESEARCH

Development of a new humanized mouse model to study acute inflammatory arthritis

(2012) Alexander V Misharin et al.   Journal of Translational Medicine

NOD/scid IL-2Rgnull mice: a preclinical model system to evaluate human dendritic cell-based vaccine strategies in vivo

(2012) Stefani Spranger et al.   Journal of Translational Medicine

Development of a Humanized HLA-A2.1/DP4 Transgenic Mouse Model and the Use of This Model to Map HLA-DP4-Restricted Epitopes of HBV Envelope Protein

(2012) Zhitao Ru et al.   PLoS One

Xenogeneic Graft-versus-Host-Disease in NOD-scid IL-2Rγnull Mice Display a T-Effector Memory Phenotype

(2012) Niwa Ali et al.   PLoS One

Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2nullIl2rγnull mouse model: A multivariable optimization approach

(2011) Julie Lang et al.   CLINICAL IMMUNOLOGY

Generation of Human Antigen-Specific Monoclonal IgM Antibodies Using Vaccinated “Human Immune System” Mice

(2010) Pablo D. Becker et al.   PLoS One

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice

(2010) L. D. Shultz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Humanized Mice for the Study of Type 1 Diabetes and Beta Cell Function

(2009) Marie King et al.   Annals of the New York Academy of Sciences

Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex

(2009) M. A. King et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The utilization of humanized mouse models for the study of human retroviral infections

(2009) Rachel Van Duyne et al.   Retrovirology

Non-obese diabetic-recombination activating gene-1 (NOD-Rag 1null) interleukin (IL)-2 receptor common gamma chain (IL 2 rγnull) null mice: a radioresistant model for human lymphohaematopoietic engraftment

(2008) T. Pearson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+B cells

(2008) Ferenc A. Scheeren et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate immune ‘self’ recognition: a role for CD47–SIRPα interactions in hematopoietic stem cell transplantation

(2008) Timo K. van den Berg et al.   TRENDS IN IMMUNOLOGY