Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy

Deimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice

(2016) Carmen Agustín-Pavón et al.   Molecular Neurodegeneration

BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activation

(2015) Gianluca Fulgenzi et al.   JOURNAL OF CELL BIOLOGY

HDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievements

(2015) Michal Mielcarek et al.   Frontiers in Cellular Neuroscience

Vascular histone deacetylation by pharmacological HDAC inhibition

(2014) Haloom Rafehi et al.   GENOME RESEARCH

The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model

(2014) Michal Mielcarek et al.   PLoS One

Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy

(2014) Patrick M. McLendon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease

(2014) Michal Mielcarek et al.   PLoS Genetics

Review and Meta-Analysis of Incidence and Clinical Predictors of Anthracycline Cardiotoxicity

(2013) Marzia Lotrionte et al.   AMERICAN JOURNAL OF CARDIOLOGY

Regulation of fetal gene expression in heart failure

(2013) Ellen Dirkx et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Histone deacetylase signaling in cardioprotection

(2013) Lorenz H. Lehmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA-22 Regulates Cardiac Hypertrophy and Remodeling in Response to Stress

(2013) Zhan-Peng Huang et al.   CIRCULATION RESEARCH

HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain In Vivo

(2013) Michal Mielcarek et al.   PLoS One

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

(2013) Michal Mielcarek et al.   PLOS BIOLOGY

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Continuous Versus Bolus Infusion of Doxorubicin in Children With ALL: Long-term Cardiac Outcomes

(2012) S. E. Lipshultz et al.   PEDIATRICS

Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model

(2012) Varsha G. Desai et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Therapeutic Potential for HDAC Inhibitors in the Heart

(2011) Timothy A. McKinsey   Annual Review of Pharmacology and Toxicology

SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease

(2011) Michal Mielcarek et al.   PLoS One

Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of β-Catenin

(2010) Andriana Margariti et al.   CIRCULATION RESEARCH

Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells

(2010) Mei-Chuan Chen et al.   HEPATOLOGY

HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

(2010) Jeffrey P. Cardinale et al.   HYPERTENSION

Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment

(2010) Claudia Colussi et al.   PHARMACOLOGICAL RESEARCH

Doxorubicin Cardiomyopathy

(2009) Kanu Chatterjee et al.   CARDIOLOGY

Targeting histone deacetylases for heart failure

(2009) Erik W Bush et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Histone deacetylase inhibition in the treatment of heart disease

(2008) Jeff M Berry et al.   Expert Opinion On Drug Safety

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

(2008) Anne Granger et al.   FASEB JOURNAL

HDAC4 and PCAF Bind to Cardiac Sarcomeres and Play a Role in Regulating Myofilament Contractile Activity

(2008) Mahesh P. Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

(2008) Rusty L. Montgomery et al.   JOURNAL OF CLINICAL INVESTIGATION

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS