The Huntington's Disease-Related Cardiomyopathy Prevents a Hypertrophic Response in the R6/2 Mouse Model

Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease

(2014) Michal Mielcarek et al.   PLoS Genetics

HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain In Vivo

(2013) Michal Mielcarek et al.   PLoS One

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

(2013) Michal Mielcarek et al.   PLOS BIOLOGY

Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Drosophila Heart

(2013) Girish C. Melkani et al.   PLoS Genetics

Neurocardiac dysregulation and neurogenic arrhythmias in a transgenic mouse model of Huntington's disease

(2012) Helen Kiriazis et al.   JOURNAL OF PHYSIOLOGY-LONDON

Therapeutic Potential for HDAC Inhibitors in the Heart

(2011) Timothy A. McKinsey   Annual Review of Pharmacology and Toxicology

SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease

(2011) Michal Mielcarek et al.   PLoS One

HDAC Inhibition Attenuates Inflammatory, Hypertrophic, and Hypertensive Responses in Spontaneously Hypertensive Rats

(2010) Jeffrey P. Cardinale et al.   HYPERTENSION

TEAD-1 Overexpression in the Mouse Heart Promotes an Age-dependent Heart Dysfunction

(2010) Richard W. Tsika et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone deacetylase inhibitors: Keeping momentum for neuromuscular and cardiovascular diseases treatment

(2010) Claudia Colussi et al.   PHARMACOLOGICAL RESEARCH

Huntington's disease: The current state of research with peripheral tissues

(2009) Jenny Sassone et al.   EXPERIMENTAL NEUROLOGY

Targeting histone deacetylases for heart failure

(2009) Erik W Bush et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease

(2009) Kirupa Sathasivam et al.   HUMAN MOLECULAR GENETICS

Beyond the brain: widespread pathology in Huntington's disease

(2009) Jorien MM van der Burg et al.   LANCET NEUROLOGY

Cardiomyocyte Expression of a Polyglutamine Preamyloid Oligomer Causes Heart Failure

(2008) J. Scott Pattison et al.   CIRCULATION

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

(2008) Anne Granger et al.   FASEB JOURNAL

VITO-2, a new SID domain protein, is expressed in the myogenic lineage during early mouse embryonic development

(2008) Michal Mielcarek et al.   GENE EXPRESSION PATTERNS

HDAC4 and PCAF Bind to Cardiac Sarcomeres and Play a Role in Regulating Myofilament Contractile Activity

(2008) Mahesh P. Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transgenic Overexpression of Hdac3 in the Heart Produces Increased Postnatal Cardiac Myocyte Proliferation but Does Not Induce Hypertrophy

(2008) Chinmay M. Trivedi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

(2008) Rusty L. Montgomery et al.   JOURNAL OF CLINICAL INVESTIGATION

Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease

(2008) Caroline L Benn et al.   Molecular Neurodegeneration