Isoflurane anesthesia promotes cognitive impairment by inducing expression of β-amyloid protein-related factors in the hippocampus of aged rats

γ-Secretase Catalyzes Sequential Cleavages of the AβPP Transmembrane Domain

(2017) Xuemin Xu   JOURNAL OF ALZHEIMERS DISEASE

Anesthesia with Isoflurane Increases Amyloid Pathology in Mice Models of Alzheimer'S Disease

(2017) Juan Perucho et al.   JOURNAL OF ALZHEIMERS DISEASE

2015 Alzheimer's disease facts and figures

(2015)   Alzheimers & Dementia

The detection of β-amyloid plaques in an Alzheimer's disease rat model with DDNP-SPIO

(2015) D. Zhang et al.   CLINICAL RADIOLOGY

Sevoflurane aggregates cognitive dysfunction and hippocampal oxidative stress induced by β-amyloid in rats

(2015) Tian Yue et al.   LIFE SCIENCES

Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

(2015) Sergio T. Ferreira et al.   Frontiers in Cellular Neuroscience

Interleukin17A Promotes Postoperative Cognitive Dysfunction by Triggering β-Amyloid Accumulation via the Transforming Growth Factor-β (TGFβ)/Smad Signaling Pathway

(2015) Ayong Tian et al.   PLoS One

Accelerated microglial pathology is associated with Aβ plaques in mouse models of Alzheimer's disease

(2014) Rona Baron et al.   AGING CELL

Amyloid Beta-Derived Diffusible Ligands (ADDLs) Induce Abnormal Expression of Insulin Receptors in Rat Hippocampal Neurons

(2014) Xin Liu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Characterization of a Brain Permeant Fluorescent Molecule and Visualization of Aβ Parenchymal Plaques, Using Real-Time Multiphoton Imaging in Transgenic Mice

(2014) G.S.M. Sundaram et al.   ORGANIC LETTERS

Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

(2013) Lei Gu et al.   JOURNAL OF NEUROCHEMISTRY

Soluble Aβ oligomer-induced synaptopathy: c-Jun N-terminal kinase's role

(2013) Alessandra Sclip et al.   Journal of Molecular Cell Biology

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Aβ Oligomers-Induced Toxicity is Attenuated in Cells Cultured with NbActiv4™ Medium

(2012) Yan Zhou et al.   NEUROTOXICITY RESEARCH

Multidentate18F-Polypegylated Styrylpyridines As Imaging Agents for Aβ Plaques in Cerebral Amyloid Angiopathy (CAA)

(2011) Zhihao Zha et al.   JOURNAL OF MEDICINAL CHEMISTRY

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

Isoflurane-induced spatial memory impairment by a mechanism independent of amyloid-beta levels and tau protein phosphorylation changes in aged rats

(2011) Weiran Liu et al.   NEUROLOGICAL RESEARCH

Isoflurane induces hippocampal cell injury and cognitive impairments in adult rats

(2011) Daowei Lin et al.   NEUROPHARMACOLOGY

The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β

(2010) Xu Wu et al.   NEUROBIOLOGY OF AGING

ADDLs and the signaling web that leads to Alzheimer’s disease

(2010) Grant A. Krafft et al.   NEUROPHARMACOLOGY

Isoflurane Differentially Affects Neurogenesis and Long-term Neurocognitive Function in 60-day-old and 7-day-old Rats

(2009) Greg Stratmann et al.   ANESTHESIOLOGY

Acceleration and persistence of neurofibrillary pathology in a mouse model of tauopathy following anesthesia

(2009) Emmanuel Planel et al.   FASEB JOURNAL

The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid β-protein level in vivo

(2008) Zhongcong Xie et al.   ANNALS OF NEUROLOGY

BACE1 Structure and Function in Health and Alzheimers Disease

(2008) Sarah Cole et al.   Current Alzheimer Research

Amyloid beta oligomers induce impairment of neuronal insulin receptors

(2007) Wei-Qin Zhao et al.   FASEB JOURNAL

Brain and behavior changes in 12-month-old Tg2576 and nontransgenic mice exposed to anesthetics

(2007) Shannon L. Bianchi et al.   NEUROBIOLOGY OF AGING