Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets
Authors
Keywords
Mitochondria, Medulloblastoma, Glycolysis, Cell metabolism, Metabolic pathways, Oxidative phosphorylation, Cancer treatment, Drug metabolism
Journal
PLoS One
Volume 12, Issue 4, Pages e0176162
Publisher
Public Library of Science (PLoS)
Online
2017-04-21
DOI
10.1371/journal.pone.0176162
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Metabolic Switches Linked to Pluripotency and Embryonic Stem Cell Differentiation
- (2015) Ng Shyh-Chang et al. Cell Metabolism
- Activation of pyruvate dehydrogenase by dichloroacetate has the potential to induce epigenetic remodeling in the heart
- (2015) Tomohiro Matsuhashi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Dichloroacetate induces autophagy in colorectal cancer cells and tumours
- (2014) G Lin et al. BRITISH JOURNAL OF CANCER
- Epidermal Growth Factor Receptor (EGFR) Signaling Regulates Global Metabolic Pathways in EGFR-mutated Lung Adenocarcinoma
- (2014) Hideki Makinoshima et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function
- (2014) Andrea Viale et al. NATURE
- Targeting Unique Metabolic Properties of Breast Tumor Initiating Cells
- (2014) Weiguo Feng et al. STEM CELLS
- Control of glioma cell death and differentiation by PKM2–Oct4 interaction
- (2014) M Morfouace et al. Cell Death & Disease
- Dichloroacetate inhibits aerobic glycolysis in multiple myeloma cells and increases sensitivity to bortezomib
- (2013) W Y Sanchez et al. BRITISH JOURNAL OF CANCER
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
- (2013) Keiyo Takubo et al. Cell Stem Cell
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- Role of Dynamin-Related Protein 1 (Drp1)-Mediated Mitochondrial Fission in Oxygen Sensing and Constriction of the Ductus Arteriosus
- (2013) Zhigang Hong et al. CIRCULATION RESEARCH
- Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission
- (2013) Willard W. Sharp et al. FASEB JOURNAL
- Energy Metabolism Characterization of a Novel Cancer Stem Cell-Like Line 3AB-OS
- (2013) Roberta Palorini et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- In vitro stemness characterization of radio-resistant clones isolated from a medulloblastoma cell line ONS-76
- (2013) Lue Sun et al. JOURNAL OF RADIATION RESEARCH
- Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3
- (2013) P. Mao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel bisbenzimide-nitroxides for nuclear redox imaging in living cells
- (2012) Mamiko Ikeda et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells
- (2012) Peter S Harris et al. BMC CANCER
- Metabolic Plasticity in Stem Cell Homeostasis and Differentiation
- (2012) Clifford D.L. Folmes et al. Cell Stem Cell
- Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint
- (2012) Tohru Yamamori et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondria-Targeted Superoxide Dismutase (SOD2) Regulates Radiation Resistance and Radiation Stress Response in HeLa Cells
- (2012) Ayaka HOSOKI et al. JOURNAL OF RADIATION RESEARCH
- Glycolytic Inhibition Alters Anaplastic Thyroid Carcinoma Tumor Metabolism and Improves Response to Conventional Chemotherapy and Radiation
- (2012) Vlad C. Sandulache et al. MOLECULAR CANCER THERAPEUTICS
- Clonal selection drives genetic divergence of metastatic medulloblastoma
- (2012) Xiaochong Wu et al. NATURE
- Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
- (2012) Toshifumi Yae et al. Nature Communications
- Molecular subgroups of medulloblastoma: the current consensus
- (2011) Michael D. Taylor et al. ACTA NEUROPATHOLOGICA
- Ionizing radiation accelerates Drp1-dependent mitochondrial fission, which involves delayed mitochondrial reactive oxygen species production in normal human fibroblast-like cells
- (2011) Shinko Kobashigawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth
- (2011) Takatsugu Ishimoto et al. CANCER CELL
- Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
- (2011) Clifford D.L. Folmes et al. Cell Metabolism
- Cancer Incidence and Incidence Rates in Japan in 2006: Based on Data from 15 Population-based Cancer Registries in the Monitoring of Cancer Incidence in Japan (MCIJ) Project
- (2011) T. Matsuda et al. JAPANESE JOURNAL OF CLINICAL ONCOLOGY
- Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts
- (2011) Sandra Varum et al. PLoS One
- MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma
- (2011) Pasqualino de Antonellis et al. PLoS One
- Mitochondrial-Associated Cell Death Mechanisms Are Reset to an Embryonic-Like State in Aged Donor-Derived iPS Cells Harboring Chromosomal Aberrations
- (2011) Alessandro Prigione et al. PLoS One
- Metabolic state of glioma stem cells and nontumorigenic cells
- (2011) E. Vlashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- What are the sources of hydrogen peroxide production by heart mitochondria?
- (2010) Vera G. Grivennikova et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Mitochondrial proton and electron leaks
- (2010) Martin Jastroch et al. Essays in Biochemistry
- Induction of in situ DNA double-strand breaks and apoptosis by 200 MeV protons and 10 MV X-rays in human tumour cell lines
- (2010) Ariungerel Gerelchuluun et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- CD13 is a therapeutic target in human liver cancer stem cells
- (2010) Naotsugu Haraguchi et al. JOURNAL OF CLINICAL INVESTIGATION
- Survival and Prognostic Factors of Early Childhood Medulloblastoma: An International Meta-Analysis
- (2010) Stefan Rutkowski et al. JOURNAL OF CLINICAL ONCOLOGY
- Medulloblastoma Comprises Four Distinct Molecular Variants
- (2010) Paul A. Northcott et al. JOURNAL OF CLINICAL ONCOLOGY
- Accumulation of CD133-positive glioma cells after high-dose irradiation by Gamma Knife surgery plus external beam radiation
- (2010) Kaoru Tamura et al. JOURNAL OF NEUROSURGERY
- Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells
- (2010) Lyle Armstrong et al. STEM CELLS
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Association of reactive oxygen species levels and radioresistance in cancer stem cells
- (2009) Maximilian Diehn et al. NATURE
- Part I General Features of Brain Tumors
- (2009) NEUROLOGIA MEDICO-CHIRURGICA
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- The metabolism of proline, a stress substrate, modulates carcinogenic pathways
- (2008) James M. Phang et al. AMINO ACIDS
- Regulation of Reactive Oxygen Species and Genomic Stability in Hematopoietic Stem Cells
- (2008) Kazuhito Naka et al. ANTIOXIDANTS & REDOX SIGNALING
- Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer
- (2008) E D Michelakis et al. BRITISH JOURNAL OF CANCER
- Medulloblastoma Stem Cells
- (2008) Xing Fan et al. JOURNAL OF CLINICAL ONCOLOGY
- Dichloroacetate (DCA) sensitizes both wild‐type and over expressingBcl‐2prostate cancer cells in vitro to radiation
- (2008) Wengang Cao et al. PROSTATE
- Tissue oxygenation in a murine SCC VII tumor after X-ray irradiation as determined by EPR spectroscopy
- (2008) Hirotada Fujii et al. RADIOTHERAPY AND ONCOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started