Conophylline inhibits non-alcoholic steatohepatitis in mice

Metabolic phenotype and adipose and liver features in a high-fat Western diet-induced mouse model of obesity-linked NAFLD

(2016) Yuwen Luo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

S100A8 Production in CXCR2-Expressing CD11b+Gr-1highCells Aggravates Hepatitis in Mice Fed a High-Fat and High-Cholesterol Diet

(2015) Kaori Mukai et al.   JOURNAL OF IMMUNOLOGY

Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet

(2014) Naoki Tanaka et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of adipose tissue in methionine–choline-deficient model of non-alcoholic steatohepatitis (NASH)

(2014) Pooja Jha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Determination of topological structure of ARL6ip1 in cells: Identification of the essential binding region of ARL6ip1 for conophylline

(2013) Masahiro Kuroda et al.   FEBS LETTERS

Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice

(2013) Ling Yang et al.   HEPATOLOGY

Conophylline suppresses hepatic stellate cells and attenuates thioacetamide-induced liver fibrosis in rats

(2013) Norio Kubo et al.   LIVER INTERNATIONAL

Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients

(2012) Pierre Bedossa et al.   HEPATOLOGY

Angiotensin II type 1 receptor antagonist prevents hepatic carcinoma in rats with nonalcoholic steatohepatitis

(2012) Yosui Tamaki et al.   JOURNAL OF GASTROENTEROLOGY

Rosuvastatin ameliorates high-fat and high-cholesterol diet-induced nonalcoholic steatohepatitis in rats

(2012) Yoshihisa Okada et al.   LIVER INTERNATIONAL

Conophylline Suppresses Pancreatic Stellate Cells and Improves Islet Fibrosis in Goto-Kakizaki Rats

(2011) Rie Saito et al.   ENDOCRINOLOGY

The metabolic syndrome

(2010) Robert H Eckel et al.   LANCET

NAFLD as a Risk Factor for the Development of Diabetes and the Metabolic Syndrome: An Eleven-Year Follow-up Study

(2009) Leon A Adams et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Antidiabetic effect of orally administered conophylline-containing plant extract on streptozotocin-treated and Goto-Kakizaki rats

(2009) Mikio Fujii et al.   BIOMEDICINE & PHARMACOTHERAPY

Dysfunctional very-low-density lipoprotein synthesis and release is a key factor in nonalcoholic steatohepatitis pathogenesis

(2009) Koji Fujita et al.   HEPATOLOGY

Telmisartan attenuates progression of steatohepatitis in mice: role of hepatic macrophage infiltration and effects on adipose tissue

(2009) Hiroshi Kudo et al.   LIVER INTERNATIONAL

Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts)

(2008) Robert Ehehalt et al.   BMC CELL BIOLOGY

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

(2008) Mary E. Rinella et al.   JOURNAL OF LIPID RESEARCH

The Epidemiology of Nonalcoholic Fatty Liver Disease: A Global Perspective

(2008) Mariana Lazo et al.   SEMINARS IN LIVER DISEASE