A novel framework for the identification of drug target proteins: Combining stacked auto-encoders with a biased support vector machine

Predicting DNA Methylation State of CpG Dinucleotide Using Genome Topological Features and Deep Networks

(2016) Yiheng Wang et al.   Scientific Reports

Benchmarking Deep Networks for Predicting Residue-Specific Quality of Individual Protein Models in CASP11

(2016) Tong Liu et al.   Scientific Reports

A Deep Learning Network Approach to ab initio Protein Secondary Structure Prediction

(2015) Matt Spencer et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

A deep learning framework for modeling structural features of RNA-binding protein targets

(2015) Sai Zhang et al.   NUCLEIC ACIDS RESEARCH

DANN: a deep learning approach for annotating the pathogenicity of genetic variants

(2014) Daniel Quang et al.   BIOINFORMATICS

SMOQ: a tool for predicting the absolute residue-specific quality of a single protein model with support vector machines

(2014) Renzhi Cao et al.   BMC BIOINFORMATICS

A Semi-Supervised Method for Drug-Target Interaction Prediction with Consistency in Networks

(2013) Hailin Chen et al.   PLoS One

Effects of protein interaction data integration, representation and reliability on the use of network properties for drug target prediction

(2012) Antonio Mora et al.   BMC BIOINFORMATICS

Protein-protein Interactions: Network Analysis and Applications in Drug Discovery

(2012) Jennyfer Bultinck et al.   CURRENT PHARMACEUTICAL DESIGN

Deep Neural Networks for Acoustic Modeling in Speech Recognition: The Shared Views of Four Research Groups

(2012) Geoffrey Hinton et al.   IEEE SIGNAL PROCESSING MAGAZINE

A Systematic Prediction of Multiple Drug-Target Interactions from Chemical, Genomic, and Pharmacological Data

(2012) Hua Yu et al.   PLoS One

Trends in the exploitation of novel drug targets

(2011) Mathias Rask-Andersen et al.   NATURE REVIEWS DRUG DISCOVERY

Principles of early drug discovery

(2010) JP Hughes et al.   BRITISH JOURNAL OF PHARMACOLOGY

DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs

(2010) C. Knox et al.   NUCLEIC ACIDS RESEARCH

Properties and identification of human protein drug targets

(2009) Tala M. Bakheet et al.   BIOINFORMATICS

Target discovery from data mining approaches

(2009) Yongliang Yang et al.   DRUG DISCOVERY TODAY

The analysis of the drug–targets based on the topological properties in the human protein–protein interaction network

(2009) Mingzhu Zhu et al.   JOURNAL OF DRUG TARGETING

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Identifying drug-target proteins based on network features

(2009) MingZhu Zhu et al.   Science in China. Series C, Life sciences / Chinese Academy of Sciences

Prediction of drug-target interaction networks from the integration of chemical and genomic spaces

(2008) Y. Yamanishi et al.   BIOINFORMATICS

Interaction networks: From protein functions to drug discovery. A review

(2008) E. Chautard et al.   PATHOLOGIE BIOLOGIE

Drug Target Identification Using Side-Effect Similarity

(2008) M. Campillos et al.   SCIENCE

Unraveling Protein Networks with Power Graph Analysis

(2008) Loïc Royer et al.   PLoS Computational Biology