Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function
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Title
Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function
Authors
Keywords
Cerebrospinal fluid, Amyotrophic lateral sclerosis, Luminescence, Cytokines, Luciferase, Motor neurons, Signal inhibition, Neurological signaling
Journal
PLoS One
Volume 12, Issue 2, Pages e0171668
Publisher
Public Library of Science (PLoS)
Online
2017-02-08
DOI
10.1371/journal.pone.0171668
References
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Note: Only part of the references are listed.- SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development
- (2016) Madalina Raducu et al. EMBO JOURNAL
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
- (2015) Ana Jovičić et al. NATURE NEUROSCIENCE
- Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex
- (2015) Eleonora Aronica et al. NEUROBIOLOGY OF DISEASE
- The dual roles of immunity in ALS: Injury overrides protection
- (2015) Benjamin J. Murdock et al. NEUROBIOLOGY OF DISEASE
- Ptch1 and Gli regulate Shh signalling dynamics via multiple mechanisms
- (2015) Michael Cohen et al. Nature Communications
- The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions
- (2014) Kenneth L. Pitter et al. GLIA
- Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kap 2 in Hedgehog signaling
- (2014) Q. Shi et al. JOURNAL OF CELL SCIENCE
- Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity
- (2014) Gabriel Olmos et al. MEDIATORS OF INFLAMMATION
- Human Motor Neurons Generated from Neural Stem Cells Delay Clinical Onset and Prolong Life in ALS Mouse Model
- (2014) Hong J. Lee et al. PLoS One
- Sonic hedgehog signalling pathway regulates apoptosis through Smo protein in human umbilical vein endothelial cells
- (2014) S.-l. Zhu et al. RHEUMATOLOGY
- Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors
- (2014) L. Katsimpardi et al. SCIENCE
- Blood-CNS Barrier Impairment in ALS patients versus an animal model
- (2014) Svitlana Garbuzova-Davis et al. Frontiers in Cellular Neuroscience
- Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice
- (2013) Xiaoxing Ma et al. BMC NEUROSCIENCE
- Decoding the phosphorylation code in Hedgehog signal transduction
- (2013) Yongbin Chen et al. CELL RESEARCH
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Differentiated NSC-34 motoneuron-like cells as experimental model for cholinergic neurodegeneration
- (2013) Oliver Maier et al. NEUROCHEMISTRY INTERNATIONAL
- Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
- (2012) Ethan A. Winkler et al. ACTA NEUROPATHOLOGICA
- Impaired blood–brain/spinal cord barrier in ALS patients
- (2012) Svitlana Garbuzova-Davis et al. BRAIN RESEARCH
- Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
- (2012) Bing Liao et al. EXPERIMENTAL NEUROLOGY
- Sonic hedgehog antagonists induce cell death in acute myeloid leukemia cells with the presence of lipopolysaccharides, tumor necrosis factor-α, or interferons
- (2012) Frank Leigh Lu et al. INVESTIGATIONAL NEW DRUGS
- TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells
- (2012) Claudia Colombrita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sonic hedgehog-Dependent Induction of MicroRNA 31 and MicroRNA 150 Regulates Mycobacterium bovis BCG-Driven Toll-Like Receptor 2 Signaling
- (2012) Devram Sampat Ghorpade et al. MOLECULAR AND CELLULAR BIOLOGY
- Sonic Hedgehog Maintains Cellular and Neurochemical Homeostasis in the Adult Nigrostriatal Circuit
- (2012) Luis E. Gonzalez-Reyes et al. NEURON
- Trappin-2/Elafin Modulate Innate Immune Responses of Human Endometrial Epithelial Cells to PolyI∶C
- (2012) Anna G. Drannik et al. PLoS One
- Gli Proteins in Development and Disease
- (2011) Chi-chung Hui et al. Annual Review of Cell and Developmental Biology
- Adenylyl Cyclase type 3, a marker of primary cilia, is reduced in primary cell culture and in lumbar spinal cord in situ in G93A SOD1 mice
- (2011) Xiaoxing Ma et al. BMC NEUROSCIENCE
- Sonic Hedgehog is Cytoprotective against Oxidative Challenge in a Cellular Model of Amyotrophic Lateral Sclerosis
- (2011) Randy Peterson et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Gdf11 Facilitates Temporal Progression of Neurogenesis in the Developing Spinal Cord
- (2011) Y. Shi et al. JOURNAL OF NEUROSCIENCE
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
- (2011) J. I. Alvarez et al. SCIENCE
- Interleukin-17 and interleukin-23 are elevated in serum and cerebrospinal fluid of patients with ALS: a reflection of Th17 cells activation?
- (2010) M. Rentzos et al. ACTA NEUROLOGICA SCANDINAVICA
- Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice
- (2010) David R. Beers et al. BRAIN BEHAVIOR AND IMMUNITY
- The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
- (2010) E. W. Humke et al. GENES & DEVELOPMENT
- Sonic Hedgehog signaling in the mammalian brain
- (2010) Elisabeth Traiffort et al. JOURNAL OF NEUROCHEMISTRY
- CSF chemokine alterations related to the clinical course of amyotrophic lateral sclerosis
- (2010) Takahisa Tateishi et al. JOURNAL OF NEUROIMMUNOLOGY
- Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
- (2010) Daryl A Bosco et al. NATURE NEUROSCIENCE
- Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development
- (2010) X. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Retrograde axonal transport: pathways to cell death?
- (2010) Eran Perlson et al. TRENDS IN NEUROSCIENCES
- TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
- (2009) Brian S. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Sonic Hedgehog Pathway Activation Is Induced by Acute Brain Injury and Regulated by Injury-Related Inflammation
- (2009) N. M. Amankulor et al. JOURNAL OF NEUROSCIENCE
- Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants
- (2009) M. Mir et al. NEUROSCIENCE
- Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-gli1 in autoimmune encephalomyelitis and multiple sclerosis
- (2008) Yue Wang et al. ANNALS OF NEUROLOGY
- Elevated Inflammatory Markers in a Group of Amyotrophic Lateral Sclerosis Patients from Northern India
- (2008) G. Nagesh Babu et al. NEUROCHEMICAL RESEARCH
- A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis
- (2008) R. M. Mitchell et al. NEUROLOGY
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