Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action

Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity

(2014) Zenita Adhireksan et al.   Nature Communications

CGGBP1 phosphorylation constitutes a telomere-protection signal

(2013) Umashankar Singh et al.   CELL CYCLE

Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle

(2013) Keiko Horiuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anticancer metallodrug research analytically painting the “omics” picture—current developments and future trends

(2012) Michael Groessl et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Targeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs

(2012) Gianni Sava et al.   DALTON TRANSACTIONS

The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics

(2012) Francesca Guidi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Combination of metallomics and proteomics to study the effects of the metallodrug RAPTA-T on human cancer cells

(2012) Dirk A. Wolters et al.   Metallomics

Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

(2012) Christian G. Hartinger et al.   ORGANOMETALLICS

Streptavidin and its biotin complex at atomic resolution

(2011) Isolde Le Trong et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CGGBP1 regulates cell cycle in cancer cells

(2011) Umashankar Singh et al.   BMC MOLECULAR BIOLOGY

A Ruthenium Antimetastasis Agent Forms Specific Histone Protein Adducts in the Nucleosome Core

(2011) Bin Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA

(2011) Filipa Mendes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anti-proliferative and pro-apoptotic actions of a novel human and mouse ovarian tumor-associated gene OTAG-12: downregulation, alternative splicing and drug sensitization

(2011) X Chen et al.   ONCOGENE

Bioorganometallics: Future Trends in Drug Discovery, Analytical Chemistry, and Catalysis†,‡

(2011) Elizabeth A. Hillard et al.   ORGANOMETALLICS

Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90

(2010) Patrick Fadden et al.   CHEMISTRY & BIOLOGY

CGGBP1 is a nuclear and midbody protein regulating abscission

(2010) Umashankar Singh et al.   EXPERIMENTAL CELL RESEARCH

Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS

(2010) Michael Groessl et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

Organometallic Anticancer Compounds

(2010) Gilles Gasser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases

(2010) Takashi MURAMATSU   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Exploring metallodrug–protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound

(2009) Angela Casini et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action

(2009) Angela Casini et al.   Metallomics

Effect of FGF-binding Protein 3 on Vascular Permeability

(2008) Wentao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ruthenium(II)–arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53–JNK pathways

(2008) Soumya Chatterjee et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

CZE–ICP-MS as a tool for studying the hydrolysis of ruthenium anticancer drug candidates and their reactivity towards the DNA model compound dGMP

(2008) Michael Groessl et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Hydrolysis study of the bifunctional antitumour compound RAPTA-C, [Ru(η6-p-cymene)Cl2(pta)]

(2008) Claudine Scolaro et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Emerging Protein Targets for Anticancer Metallodrugs: Inhibition of Thioredoxin Reductase and Cathepsin B by Antitumor Ruthenium(II)−Arene Compounds

(2008) Angela Casini et al.   JOURNAL OF MEDICINAL CHEMISTRY