Development of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model

History of the G Protein–Coupled Receptor (GPCR) Assays From Traditional to a State-of-the-Art Biosensor Assay

(2014) Kanako Miyano et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Randomized clinical trial: rikkunshito in the treatment of functional dyspepsia-a multicenter, double-blind, randomized, placebo-controlled study

(2014) H. Suzuki et al.   NEUROGASTROENTEROLOGY AND MOTILITY

New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line

(2013) Kiyoshi Terawaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Inhibitory Effects of Isoflavones on Tumor Growth and Cachexia in Newly Established Cachectic Mouse Models Carrying Human Stomach Cancers

(2013) Kazuyoshi Yanagihara et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

The gene expression of the hypothalamic feeding-regulating peptides in cisplatin-induced anorexic rats

(2013) Mitsuhiro Yoshimura et al.   PEPTIDES

Intragastric administration of rikkunshito stimulates upper gastrointestinal motility and gastric emptying in conscious dogs

(2012) Mitsuhiro Yanai et al.   JOURNAL OF GASTROENTEROLOGY

Changes in the melanocortin receptors in the hypothalamus of a rat model of cancer cachexia

(2012) Masami Suzuki et al.   SYNAPSE

Potentiation of ghrelin signaling attenuates cancer anorexia–cachexia and prolongs survival

(2011) N Fujitsuka et al.   Translational Psychiatry

Comparing Label-Free Biosensors for Pharmacological Screening With Cell-Based Functional Assays

(2010) Matthew F. Peters et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Label-free whole-cell assays: expanding the scope of GPCR screening

(2010) Clay W Scott et al.   DRUG DISCOVERY TODAY

Rikkunshito and 5-HT2C receptor antagonist improve cisplatin-induced anorexia via hypothalamic ghrelin interaction

(2010) Koji Yakabi et al.   REGULATORY PEPTIDES

Arcuate Nucleus Proopiomelanocortin Neurons Mediate the Acute Anorectic Actions of Leukemia Inhibitory Factor via gp130

(2009) Aaron J. Grossberg et al.   ENDOCRINOLOGY

The Traditional Japanese Medicine Rikkunshito Promotes Gastric Emptying via the Antagonistic Action of the 5-HT3Receptor Pathway in Rats

(2009) K. Tominaga et al.   Evidence-based Complementary and Alternative Medicine

The traditional Japanese medicine Rikkunshito increases the plasma level of ghrelin in humans and mice

(2009) Tomoaki Matsumura et al.   JOURNAL OF GASTROENTEROLOGY

Japanese herbal medicine in functional gastrointestinal disorders

(2009) h. suzuki et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Mechanisms of Cancer Cachexia

(2009) Michael J. Tisdale   PHYSIOLOGICAL REVIEWS

Selective Serotonin Reuptake Inhibitors Modify Physiological Gastrointestinal Motor Activities via 5-HT2c Receptor and Acyl Ghrelin

(2008) Naoki Fujitsuka et al.   BIOLOGICAL PSYCHIATRY

Cachexia: A new definition

(2008) William J. Evans et al.   CLINICAL NUTRITION

Rikkunshito, an Herbal Medicine, Suppresses Cisplatin-Induced Anorexia in Rats Via 5-HT2 Receptor Antagonism

(2008) Hiroshi Takeda et al.   GASTROENTEROLOGY