Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Neurotrophic effects of progranulin in vivo in reversing motor neuron defects caused by over or under expression of TDP-43 or FUS
Authors
Keywords
-
Journal
PLoS One
Volume 12, Issue 3, Pages e0174784
Publisher
Public Library of Science (PLoS)
Online
2017-03-31
DOI
10.1371/journal.pone.0174784
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
- (2015) Xiaolai Zhou et al. JOURNAL OF CELL BIOLOGY
- Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
- (2015) Jonathan D Rohrer et al. LANCET NEUROLOGY
- Genetic compensation induced by deleterious mutations but not gene knockdowns
- (2015) Andrea Rossi et al. NATURE
- Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology
- (2015) Barbara Solchenberger et al. PLoS One
- TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD
- (2015) J. P. Ling et al. SCIENCE
- Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models
- (2014) S Sakura Minami et al. NATURE MEDICINE
- Progranulin Gene Delivery Protects Dopaminergic Neurons in a Mouse Model of Parkinson’s Disease
- (2014) Jackalina M. Van Kampen et al. PLoS One
- Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice
- (2014) Yoshinori Tanaka et al. Acta Neuropathologica Communications
- Progranulin promotes activation of microglia/macrophage after pilocarpine-induced status epilepticus
- (2013) Shanshan Zhu et al. BRAIN RESEARCH
- Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish
- (2013) Channa A.A. Hewamadduma et al. HUMAN MOLECULAR GENETICS
- Disease Animal Models of TDP-43 Proteinopathy and Their Pre-Clinical Applications
- (2013) Yu-Chih Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dissociation of Frontotemporal Dementia-Related Deficits and Neuroinflammation in Progranulin Haploinsufficient Mice
- (2013) A. J. Filiano et al. JOURNAL OF NEUROSCIENCE
- Progranulin does not affect motor neuron degeneration in mutant SOD1 mice and rats
- (2013) Sarah Herdewyn et al. NEUROBIOLOGY OF AGING
- The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding
- (2013) Louis De Muynck et al. NEUROBIOLOGY OF AGING
- Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models
- (2012) Arnaud Tauffenberger et al. HUMAN MOLECULAR GENETICS
- Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury
- (2012) Lauren Herl Martens et al. JOURNAL OF CLINICAL INVESTIGATION
- RNA-mediated toxicity in neurodegenerative disease
- (2012) Veronique V. Belzil et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice
- (2012) Y. Tanaka et al. NEUROSCIENCE
- Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling
- (2011) Jindong Xu et al. NEUROBIOLOGY OF AGING
- FUS and TDP43 genetic variability in FTD and CBS
- (2011) Edward D. Huey et al. NEUROBIOLOGY OF AGING
- Synaptic dysfunction in progranulin-deficient mice
- (2011) Terri L. Petkau et al. NEUROBIOLOGY OF DISEASE
- Core features of frontotemporal dementia recapitulated in progranulin knockout mice
- (2011) N. Ghoshal et al. NEUROBIOLOGY OF DISEASE
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
- (2011) A. W. Kao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FUS and TARDBP but Not SOD1 Interact in Genetic Models of Amyotrophic Lateral Sclerosis
- (2011) Edor Kabashi et al. PLoS Genetics
- Progranulin deficiency leads to enhanced cell vulnerability and TDP-43 translocation in primary neuronal cultures
- (2010) Aobo Guo et al. BRAIN RESEARCH
- Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia
- (2010) Fangfang Yin et al. FASEB JOURNAL
- Increased caspase activation and decreased TDP-43 solubility in progranulin knockout cortical cultures
- (2010) Gernot Kleinberger et al. JOURNAL OF NEUROCHEMISTRY
- Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review
- (2010) H. Seelaar et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Microglial Upregulation of Progranulin as a Marker of Motor Neuron Degeneration
- (2010) Thomas Philips et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
- (2010) Ian RA Mackenzie et al. LANCET NEUROLOGY
- Progranulin modulates zebrafish motoneuron development in vivo and rescues truncation defects associated with knockdown of Survival motor neuron 1
- (2010) Babykumari P Chitramuthu et al. Molecular Neurodegeneration
- Progranulin is Neurotrophic In Vivo and Protects against a Mutant TDP-43 Induced Axonopathy
- (2010) Angela S. Laird et al. PLoS One
- Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β
- (2010) Xue Gao et al. Protein & Cell
- The granulin gene family: from cancer to dementia
- (2009) Andrew Bateman et al. BIOESSAYS
- Progranulin is expressed within motor neurons and promotes neuronal cell survival
- (2009) Cara L Ryan et al. BMC NEUROSCIENCE
- Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
- (2009) Edor Kabashi et al. HUMAN MOLECULAR GENETICS
- Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
- (2009) Fangfang Yin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TDP-43 is recruited to stress granules in conditions of oxidative insult
- (2009) Claudia Colombrita et al. JOURNAL OF NEUROCHEMISTRY
- The heritability and genetics of frontotemporal lobar degeneration
- (2009) J. D. Rohrer et al. NEUROLOGY
- Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations
- (2008) Ian R. A. Mackenzie et al. ACTA NEUROPATHOLOGICA
- Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury
- (2008) Katie Moisse et al. BRAIN RESEARCH
- Granulin mutations associated with frontotemporal lobar degeneration and related disorders: An update
- (2008) I. Gijselinck et al. HUMAN MUTATION
- Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
- (2008) Philip Van Damme et al. JOURNAL OF CELL BIOLOGY
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started