Examining Sources of Error in PCR by Single-Molecule Sequencing

High-specificity detection of rare alleles with Paired-End Low Error Sequencing (PELE-Seq)

(2016) Jessica L. Preston et al.   BMC GENOMICS

Polymerase specific error rates and profiles identified by single molecule sequencing

(2016) Matthew S. Hestand et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Mapping DNA polymerase errors by single-molecule sequencing

(2016) David F. Lee et al.   NUCLEIC ACIDS RESEARCH

Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing

(2016) Margaret L. Hoang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic evolutionary origin of a proofreading reverse transcriptase

(2016) J. W. Ellefson et al.   SCIENCE

Benefits and Challenges with Applying Unique Molecular Identifiers in Next Generation Sequencing to Detect Low Frequency Mutations

(2016) Ruqin Kou et al.   PLoS One

Somatic mutation in cancer and normal cells

(2015) I. Martincorena et al.   SCIENCE

Next-generation sequencing can revealin vitro-generated PCR crossover products: some artifactual sequences correspond to HLA alleles in the IMGT/HLA database

(2013) C. L. Holcomb et al.   TISSUE ANTIGENS

Detection of ultra-rare mutations by next-generation sequencing

(2012) M. W. Schmitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing

(2012) H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reducing the Effects of PCR Amplification and Sequencing Artifacts on 16S rRNA-Based Studies

(2011) Patrick D. Schloss et al.   PLoS One

Detection and quantification of rare mutations with massively parallel sequencing

(2011) I. Kinde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reducing chimera formation during PCR amplification to ensure accurate genotyping

(2010) R.P. Smyth et al.   GENE

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS