Dissection of TALE-dependent gene activation reveals that they induce transcription cooperatively and in both orientations

TAL Effectors Drive Transcription Bidirectionally in Plants

(2017) Li Wang et al.   Molecular Plant

The intergenic region of the maize defensin-like protein genesDef1 and Def2functions as an embryo-specific asymmetric bidirectional promoter

(2016) Xiaoqing Liu et al.   JOURNAL OF EXPERIMENTAL BOTANY

Targeted promoter editing for rice resistance toXanthomonas oryzaepv.oryzaereveals differential activities forSWEET14-inducing TAL effectors

(2016) Servane Blanvillain-Baufumé et al.   PLANT BIOTECHNOLOGY JOURNAL

The broadly effective recessive resistance genexa5of rice is a virulence effector-dependent quantitative trait for bacterial blight

(2016) Sheng Huang et al.   PLANT JOURNAL

A host basal transcription factor is a key component for infection of rice by TALE-carrying bacteria

(2016) Meng Yuan et al.   eLife

Molecular recognition of avirulence protein (avrxa5) by eukaryotic transcription factor xa5 of rice (Oryza sativa L.): Insights from molecular dynamics simulations

(2015) Budheswar Dehury et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

The upstream regulatory sequence of the light harvesting complex Lhcf2 gene of the marine diatom Phaeodactylum tricornutum enhances transcription in an orientation- and distance-independent fashion

(2015) Monia Teresa Russo et al.   Marine Genomics

Bidirectional Transcription Arises from Two Distinct Hubs of Transcription Factor Binding and Active Chromatin

(2015) Benjamin S. Scruggs et al.   MOLECULAR CELL

XA23 Is an Executor R Protein and Confers Broad-Spectrum Disease Resistance in Rice

(2015) Chunlian Wang et al.   Molecular Plant

A split-Cas9 architecture for inducible genome editing and transcription modulation

(2015) Bernd Zetsche et al.   NATURE BIOTECHNOLOGY

A library of synthetic transcription activator-like effector-activated promoters for coordinated orthogonal gene expression in plants

(2015) Kathleen Brückner et al.   PLANT JOURNAL

Gene targeting by the TAL effector PthXo2 reveals cryptic resistance gene for bacterial blight of rice

(2015) Junhui Zhou et al.   PLANT JOURNAL

Direct observation of TALE protein dynamics reveals a two-state search mechanism

(2015) Luke Cuculis et al.   Nature Communications

TALE activators regulate gene expression in a position- and strand-dependent manner in mammalian cells

(2014) Claudia Uhde-Stone et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of putative TAL effector targets of the citrus canker pathogens shows functional convergence underlying disease development and defense response

(2014) Andre LA Pereira et al.   BMC GENOMICS

RiceMtN3/saliva/SWEETgene family: Evolution, expression profiling, and sugar transport

(2014) Meng Yuan et al.   Journal of Integrative Plant Biology

Xanthomonas axonopodis Virulence Is Promoted by a Transcription Activator-Like Effector–Mediated Induction of a SWEET Sugar Transporter in Cassava

(2014) Megan Cohn et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

TAL effectors - pathogen strategies and plant resistance engineering

(2014) Jens Boch et al.   NEW PHYTOLOGIST

Engineered TAL Effector modulators for the large-scale gain-of-function screening

(2014) Hanshuo Zhang et al.   NUCLEIC ACIDS RESEARCH

RNA-guided transcriptional regulationin plantavia synthetic dCas9-based transcription factors

(2014) Agnieszka Piatek et al.   PLANT BIOTECHNOLOGY JOURNAL

Activation of Silenced Cytokine Gene Promoters by the Synergistic Effect of TBP-TALE and VP64-TALE Activators

(2014) Kim Anthony et al.   PLoS One

Bidirectional promoters in seed development and related hormone/stress responses

(2013) Sofia Kourmpetli et al.   BMC PLANT BIOLOGY

Rice MtN3/Saliva/SWEET Family Genes and Their Homologs in Cellular Organisms

(2013) Meng Yuan et al.   Molecular Plant

The broad bacterial blight resistance of rice line CBB23 is triggered by a novel transcription activator-like (TAL) effector ofXanthomonas oryzaepv.oryzae

(2013) Chun-Lian Wang et al.   MOLECULAR PLANT PATHOLOGY

Robust, synergistic regulation of human gene expression using TALE activators

(2013) Morgan L Maeder et al.   NATURE METHODS

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

(2013) Pablo Perez-Pinera et al.   NATURE METHODS

Five phylogenetically close riceSWEETgenes confer TAL effector-mediated susceptibility toXanthomonas oryzaepv.oryzae

(2013) Jana Streubel et al.   NEW PHYTOLOGIST

Citrus MAF1, a Repressor of RNA Polymerase III, Binds the Xanthomonas citri Canker Elicitor PthA4 and Suppresses Citrus Canker Development

(2013) A. S. Soprano et al.   PLANT PHYSIOLOGY

An Intergenic Region Shared by At4g35985 and At4g35987 in Arabidopsis thaliana Is a Tissue Specific and Stress Inducible Bidirectional Promoter Analyzed in Transgenic Arabidopsis and Tobacco Plants

(2013) Joydeep Banerjee et al.   PLoS One

Genome-Wide Computational Prediction and Analysis of Core Promoter Elements across Plant Monocots and Dicots

(2013) Sunita Kumari et al.   PLoS One

TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins

(2013) Erin L. Doyle et al.   TRENDS IN CELL BIOLOGY

Computational Predictions Provide Insights into the Biology of TAL Effector Target Sites

(2013) Jan Grau et al.   PLoS Computational Biology

Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region

(2012) Haishan Gao et al.   CELL RESEARCH

Overcoming Transcription Activator-like Effector (TALE) DNA Binding Domain Sensitivity to Cytosine Methylation

(2012) Julien Valton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distant Activation of Transcription: Mechanisms of Enhancer Action

(2012) O. I. Kulaeva et al.   MOLECULAR AND CELLULAR BIOLOGY

Top 10 plant pathogenic bacteria in molecular plant pathology

(2012) JOHN MANSFIELD et al.   MOLECULAR PLANT PATHOLOGY

TAL effector RVD specificities and efficiencies

(2012) Jana Streubel et al.   NATURE BIOTECHNOLOGY

Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

(2012) Karen Adelman et al.   NATURE REVIEWS GENETICS

Addition of transcription activator-like effector binding sites to a pathogen strain-specific rice bacterial blight resistance gene makes it effective against additional strains and against bacterial leaf streak

(2012) Aaron W. Hummel et al.   NEW PHYTOLOGIST

Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers

(2012) Sebastian Bultmann et al.   NUCLEIC ACIDS RESEARCH

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

(2012) Erin L. Doyle et al.   NUCLEIC ACIDS RESEARCH

The TAL Effector PthA4 Interacts with Nuclear Factors Involved in RNA-Dependent Processes Including a HMG Protein That Selectively Binds Poly(U) RNA

(2012) Tiago Antonio de Souza et al.   PLoS One

TAL Effectors Target the C-Terminal Domain of RNA Polymerase II (CTD) by Inhibiting the Prolyl-Isomerase Activity of a CTD-Associated Cyclophilin

(2012) Mariane Noronha Domingues et al.   PLoS One

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

(2012) A. N.-S. Mak et al.   SCIENCE

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

(2012) D. Deng et al.   SCIENCE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Divergent transcription: A new feature of active promoters

(2011) Amy C. Seila et al.   CELL CYCLE

Colonization of Rice Leaf Blades by an African Strain of Xanthomonas oryzae pv. oryzae Depends on a New TAL Effector That Induces the Rice Nodulin-3 Os11N3 Gene

(2011) Yanhua Yu et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

XanthomonasAvrBs3 Family-Type III Effectors: Discovery and Function

(2010) Jens Boch et al.   Annual Review of Phytopathology

Sugar transporters for intercellular exchange and nutrition of pathogens

(2010) Li-Qing Chen et al.   NATURE

Promoter elements of rice susceptibility genes are bound and activated by specific TAL effectors from the bacterial blight pathogen, Xanthomonas oryzae pv. oryzae

(2010) Patrick Römer et al.   NEW PHYTOLOGIST

Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3

(2010) G. Antony et al.   PLANT CELL

Searching for bidirectional promoters in Arabidopsis thaliana

(2009) Quan Wang et al.   BMC BIOINFORMATICS

Genome-wide analysis of rice (Oryza sativa L. subsp. japonica) TATA box and Y Patch promoter elements

(2009) P. Civáň et al.   GENOME

Detailed analysis of the DNA recognition motifs of theXanthomonastype III effectors AvrBs3 and AvrBs3Δrep16

(2009) Sabine Kay et al.   PLANT JOURNAL

Recognition of AvrBs3-Like Proteins Is Mediated by Specific Binding to Promoters of Matching Pepper Bs3 Alleles

(2009) P. Romer et al.   PLANT PHYSIOLOGY

Host and Pathogen Factors Controlling the Rice-Xanthomonas oryzae Interaction

(2009) F. F. White et al.   PLANT PHYSIOLOGY

The intergenic region of Arabidopsis thaliana cab1 and cab2 divergent genes functions as a bidirectional promoter

(2009) Anish Mitra et al.   PLANTA

A single plant resistance gene promoter engineered to recognize multiple TAL effectors from disparate pathogens

(2009) P. Romer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

(2009) J. Boch et al.   SCIENCE

A Simple Cipher Governs DNA Recognition by TAL Effectors

(2009) M. J. Moscou et al.   SCIENCE

Characterization of AvrHah1, a novel AvrBs3-like effector fromXanthomonas gardneriwith virulence and avirulence activity

(2008) Sebastian Schornack et al.   NEW PHYTOLOGIST

Divergent Transcription from Active Promoters

(2008) Amy C. Seila et al.   SCIENCE