Overcoming Transcription Activator-like Effector (TALE) DNA Binding Domain Sensitivity to Cytosine Methylation
Published 2012 View Full Article
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Title
Overcoming Transcription Activator-like Effector (TALE) DNA Binding Domain Sensitivity to Cytosine Methylation
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 46, Pages 38427-38432
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2012-09-30
DOI
10.1074/jbc.c112.408864
References
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- The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target
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- DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing
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- Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types
- (2011) Michael J. Ziller et al. PLoS Genetics
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- Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
- (2010) María Berdasco et al. DEVELOPMENTAL CELL
- Targeting DNA Double-Strand Breaks with TAL Effector Nucleases
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- Conserved role of intragenic DNA methylation in regulating alternative promoters
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- The repeat domain of the type III effector protein PthA shows a TPR-like structure and undergoes conformational changes upon DNA interaction
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- Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease
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- A Simple Cipher Governs DNA Recognition by TAL Effectors
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