Alterations in estrogen signalling pathways upon acquisition of anthracycline resistance in breast tumor cells

Aldo-keto reductase 1C3 (AKR1C3) is associated with the doxorubicin resistance in human breast cancer via PTEN Loss

(2015) Ting Zhong et al.   BIOMEDICINE & PHARMACOTHERAPY

Form and Function: how Estrogen and Progesterone Regulate the Mammary Epithelial Hierarchy

(2015) Lisa M. Arendt et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Continued value of adjuvant anthracyclines as treatment for early breast cancer

(2015) Natalie Turner et al.   LANCET ONCOLOGY

Induction of aldo-keto reductases (AKR1C1 and AKR1C3) abolishes the efficacy of daunorubicin chemotherapy for leukemic U937 cells

(2014) Toshiyuki Matsunaga et al.   ANTI-CANCER DRUGS

Anthracycline resistance mediated by reductive metabolism in cancer cells: The role of aldo-keto reductase 1C3

(2014) Jakub Hofman et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Endocrine Therapy for Advanced/Metastatic Breast Cancer

(2013) Gaia Schiavon et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Estrogen receptor beta 2 is associated with poor prognosis in estrogen receptor alpha-negative breast carcinoma

(2013) Νiki Ι. Chantzi et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Hormone-regulated transcriptomes: Lessons learned from estrogen signaling pathways in breast cancer cells

(2013) Nasun Hah et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Comparative Cardiac Toxicity of Anthracyclines In Vitro and In Vivo in the Mouse

(2013) Stefano Toldo et al.   PLoS One

Role of aldo–keto reductase family 1 (AKR1) enzymes in human steroid metabolism

(2013) Tea Lanišnik Rižner et al.   STEROIDS

Role of aldo-keto reductases and other doxorubicin pharmacokinetic genes in doxorubicin resistance, DNA binding, and subcellular localization

(2012) Allan D Heibein et al.   BMC CANCER

Adriamycin dose and time effects on cell cycle, cell death, and reactive oxygen species generation in leukaemia cells

(2012) Julien Savatier et al.   LEUKEMIA RESEARCH

Regulation of the Autophagic Bcl-2/Beclin 1 Interaction

(2012) Jean-Paul Decuypere et al.   Cells

Phosphorylation of Estrogen Receptor α at Serine 118 Directs Recruitment of Promoter Complexes and Gene-Specific Transcription

(2011) Tamika T. Duplessis et al.   ENDOCRINOLOGY

Estrogen Receptor and Progesterone Receptor As Predictive Biomarkers of Response to Endocrine Therapy: A Prospectively Powered Pathology Study in the Tamoxifen and Exemestane Adjuvant Multinational Trial

(2011) John M.S. Bartlett et al.   JOURNAL OF CLINICAL ONCOLOGY

Furanodienone inhibits cell proliferation and survival by suppressing ERα signaling in human breast cancer MCF-7 cells

(2010) Ying-Wei Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Neoadjuvant endocrine therapy for breast cancer: past, present and future

(2009) Agustí Barnadas et al.   ANTI-CANCER DRUGS

Change in the hormone receptor status following administration of neoadjuvant chemotherapy and its impact on the long-term outcome in patients with primary breast cancer

(2009) T Hirata et al.   BRITISH JOURNAL OF CANCER

Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer

(2009) Michael C. Byrns et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Induction of 1C aldoketoreductases and other drug dose-dependent genes upon acquisition of anthracycline resistance

(2009) Zachary W. Veitch et al.   Pharmacogenetics and Genomics

Role of drug transporters and drug accumulation in the temporal acquisition of drug resistance

(2008) Stacey L Hembruff et al.   BMC CANCER

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

(2008) S. N. Sundar et al.   CARCINOGENESIS

Aromatase Inhibitors for Breast Cancer: Proven Efficacy Across the Spectrum of Disease

(2008) Christina I. Herold et al.   Clinical Breast Cancer

The Aldo-Keto Reductase Superfamily and its Role in Drug Metabolism and Detoxification

(2008) Oleg A. Barski et al.   DRUG METABOLISM REVIEWS

The role of endocrine therapies in reducing risk of recurrence in postmenopausal women with hormone receptor-positive breast cancer

(2008) Emma Pennery   European Journal of Oncology Nursing

MNAR plays an important role in ERa activation of Src/MAPK and PI3K/Akt signaling pathways

(2008) B CHESKIS et al.   STEROIDS

Intracrinology of estrogens and androgens in breast carcinoma

(2007) Hironobu Sasano et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY