Potent Effects of Flavonoid Nobiletin on Amplitude, Period, and Phase of the Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblasts

Nobiletin promotes antioxidant and anti-inflammatory responses and elicits protection against ischemic stroke in vivo

(2016) Lan Zhang et al.   BRAIN RESEARCH

The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome

(2016) Baokun He et al.   Cell Metabolism

Nobiletin attenuates cardiac dysfunction, oxidative stress, and inflammatory in streptozotocin: induced diabetic cardiomyopathy

(2016) Ning Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Caffeine promotes anti-tumor immune response during tumor initiation: Involvement of the adenosine A2A receptor

(2015) Hadar Eini et al.   BIOCHEMICAL PHARMACOLOGY

Nobiletin Stimulates Chloride Secretion in Human Bronchial Epithelia via a cAMP/PKA-Dependent Pathway

(2015) Yuan Hao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Chronic consumption of dietary proanthocyanidins modulates peripheral clocks in healthy and obese rats

(2015) A. Ribas-Latre et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Dietary proanthocyanidins modulate melatonin levels in plasma and the expression pattern of clock genes in the hypothalamus of rats

(2015) Aleix Ribas-Latre et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Anti-inflammatory effects of 4′-demethylnobiletin, a major metabolite of nobiletin

(2015) Xian Wu et al.   Journal of Functional Foods

Entrainment of mouse peripheral circadian clocks to

(2015) Yutaro Hamaguchi et al.   Scientific Reports

Dietary proanthocyanidins modulate BMAL1 acetylation, Nampt expression and NAD levels in rat liver

(2015) Aleix Ribas-Latre et al.   Scientific Reports

Effects of caffeine on circadian phase, amplitude and period evaluated in cellsin vitroand peripheral organsin vivoin PER2::LUCIFERASE mice

(2014) Seira Narishige et al.   BRITISH JOURNAL OF PHARMACOLOGY

New Insights Into the Pharmacological Potential of Plant Flavonoids in the Catecholamine System

(2014) Nobuyuki Yanagihara et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Effect of Quetiapine on Per1, Per2, and Bmal1 Clock Gene Expression in the Mouse Amygdala and Hippocampus

(2014) Shunpei Moriya et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

REV-ERB and ROR nuclear receptors as drug targets

(2014) Douglas J. Kojetin et al.   NATURE REVIEWS DRUG DISCOVERY

Sonochemical Effects on 14 Flavonoids Common in Citrus: Relation to Stability

(2014) Liping Qiao et al.   PLoS One

A circadian gene expression atlas in mammals: Implications for biology and medicine

(2014) Ray Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Where do health benefits of flavonoids come from? Insights from flavonoid targets and their evolutionary history

(2013) Ming-Feng Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effects of resveratrol on changes induced by high-fat feeding on clock genes in rats

(2013) Jonatan Miranda et al.   BRITISH JOURNAL OF NUTRITION

Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action

(2013) Ichiro Kawahata et al.   JOURNAL OF NEURAL TRANSMISSION

The nuclear receptor Rev-erbα controls circadian thermogenic plasticity

(2013) Zachary Gerhart-Hines et al.   NATURE

How to fix a broken clock

(2013) Analyne M. Schroeder et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Small molecule modifiers of circadian clocks

(2012) Zheng Chen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

In Vivo Monitoring of Peripheral Circadian Clocks in the Mouse

(2012) Yu Tahara et al.   CURRENT BIOLOGY

Regulation of MAPK/ERK Signaling and Photic Entrainment of the Suprachiasmatic Nucleus Circadian Clock by Raf Kinase Inhibitor Protein

(2012) G. Antoun et al.   JOURNAL OF NEUROSCIENCE

Nobiletin improves obesity and insulin resistance in high-fat diet-induced obese mice

(2012) Young-Sil Lee et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

(2010) David K. Welsh et al.   Annual Review of Physiology

Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock

(2010) Y. Lee et al.   JOURNAL OF CELL SCIENCE

Resveratrol Regulates Circadian Clock Genes in Rat-1 Fibroblast Cells

(2008) Hideaki OIKE et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and A  Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2008) H. Onozuka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Maternal Feeding Controls Fetal Biological Clock

(2008) Hidenobu Ohta et al.   PLoS One