AS1411-Induced Growth Inhibition of Glioma Cells by Up-Regulation of p53 and Down-Regulation of Bcl-2 and Akt1 via Nucleolin
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
AS1411-Induced Growth Inhibition of Glioma Cells by Up-Regulation of p53 and Down-Regulation of Bcl-2 and Akt1 via Nucleolin
Authors
Keywords
Glioma cells, Cancer treatment, Apoptosis, Glioma, Small interfering RNAs, Cell cycle and cell division, Cell staining, Messenger RNA
Journal
PLoS One
Volume 11, Issue 12, Pages e0167094
Publisher
Public Library of Science (PLoS)
Online
2016-12-02
DOI
10.1371/journal.pone.0167094
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- miR-409-3p suppresses breast cancer cell growth and invasion by targeting Akt1
- (2016) Guoqiang Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell
- (2016) Rosalba Perrone et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Quantitative proteomic analysis shows differentially expressed HSPB1 in glioblastoma as a discriminating short from long survival factor and NOVA1 as a differentiation factor between low-grade astrocytoma and oligodendroglioma
- (2015) Marcela Gimenez et al. BMC CANCER
- Imp2 regulates GBM progression by activating IGF2/PI3K/Akt pathway
- (2015) Qingchun Mu et al. CANCER BIOLOGY & THERAPY
- Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma
- (2015) Yona Goldshmit et al. Oncotarget
- A dual functional fluorescent probe for glioma imaging mediated by Blood-brain barrier penetration and glioma cell targeting
- (2014) Hongwei Ma et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- In vitro and in vivo Evaluation of Antitumor Drug-Loaded Aptamer Targeted Single-Walled Carbon Nanotubes System
- (2014) Huijuan Zhang et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- DNA and RNA Quadruplex-Binding Proteins
- (2014) Václav Brázda et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cell Surface Nucleolin as a Target for Anti-Cancer Therapies
- (2014) Marina Koutsioumpa et al. Recent Patents on Anti-Cancer Drug Discovery
- Study and evaluation of mechanisms of dual targeting drug delivery system with tumor microenvironment assays compared with normal assays
- (2013) Huile Gao et al. Acta Biomaterialia
- Nucleolar control of p53: a cellular Achilles’ heel and a target for cancer therapy
- (2013) Nikolina Vlatković et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma
- (2013) Jonathan E. Rosenberg et al. INVESTIGATIONAL NEW DRUGS
- In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation
- (2013) Flavia Pichiorri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Knocking down nucleolin expression in gliomas inhibits tumor growth and induces cell cycle arrest
- (2012) Zhiqiang Xu et al. JOURNAL OF NEURO-ONCOLOGY
- RNA-binding protein nucleolin in disease
- (2012) Kotb Abdelmohsen et al. RNA Biology
- Insights into the biomedical effects of carboxylated single-wall carbon nanotubes on telomerase and telomeres
- (2012) Yong Chen et al. Nature Communications
- Akt signalling in health and disease
- (2011) Ingeborg Hers et al. CELLULAR SIGNALLING
- Glycosilated nucleolin as marker for human gliomas
- (2011) R. Galzio et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Enhanced translation by Nucleolin via G-rich elements in coding and non-coding regions of target mRNAs
- (2011) Kotb Abdelmohsen et al. NUCLEIC ACIDS RESEARCH
- MicroRNA-34a: A Novel Tumor Suppressor in p53-mutant Glioma Cell Line U251
- (2010) Shihai Luan et al. ARCHIVES OF MEDICAL RESEARCH
- Post-transcriptional and post-translational regulation of Bcl2: Figure 1
- (2010) Shaun Willimott et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Nucleolin on the Cell Surface as a New Molecular Target for Gastric Cancer Treatment
- (2010) Tatsuro Watanabe et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Mechanism of Regulation ofbcl-2mRNA by Nucleolin and A+U-rich Element-binding Factor 1 (AUF1)
- (2010) Daniella Ishimaru et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
- (2009) Paula J. Bates et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Oncogenic EGFR Signaling Networks in Glioma
- (2009) P. H. Huang et al. Science Signaling
- The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells
- (2008) S. Soundararajan et al. CANCER RESEARCH
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now