Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B

The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus

(2015) Seiichi Sato et al.   IMMUNITY

Targeted Induction of Interferon-λ in Humanized Chimeric Mouse Liver Abrogates Hepatotropic Virus Infection

(2013) Shin-ichiro Nakagawa et al.   PLoS One

Transcriptomic analysis of the woodchuck model of chronic hepatitis B

(2012) Simon P. Fletcher et al.   HEPATOLOGY

Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B

(2012) Simon P. Fletcher et al.   HEPATOLOGY

IFN-α inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome

(2012) Laura Belloni et al.   JOURNAL OF CLINICAL INVESTIGATION

Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs

(2010) John E. Coughlin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Temporal Analysis of Early Immune Responses in Patients With Acute Hepatitis B Virus Infection

(2009) Claire Dunn et al.   GASTROENTEROLOGY

Activation of innate immune antiviral responses by Nod2

(2009) Ahmed Sabbah et al.   NATURE IMMUNOLOGY

Antiviral Effects of Lamivudine, Emtricitabine, Adefovir Dipivoxil, and Tenofovir Disoproxil Fumarate Administered Orally Alone and in Combination to Woodchucks with Chronic Woodchuck Hepatitis Virus Infection

(2008) S. Menne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

(2008) Bo Zhong et al.   IMMUNITY

Innate immunity to virus infection

(2008) Osamu Takeuchi et al.   IMMUNOLOGICAL REVIEWS