Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines, Nrf-2 and the NO−cGMP−PKG−KATPChannel Signaling Pathway

Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain

(2016) Ana C. Zarpelon et al.   FASEB JOURNAL

The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2

(2015) N.A. Maioli et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ROS-mediated NF-κB and P53 signaling pathways

(2015) Yassine Chtourou et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Molecular basis of oxidative stress in gouty arthropathy

(2015) Yessica Zamudio-Cuevas et al.   CLINICAL RHEUMATOLOGY

Interleukin-10 limits intense acute swimming-induced muscle mechanical hyperalgesia in mice

(2015) Sergio M. Borghi et al.   EXPERIMENTAL PHYSIOLOGY

Curcumin inhibits superoxide anion-induced pain-like behavior and leukocyte recruitment by increasing Nrf2 expression and reducing NF-κB activation

(2015) Victor Fattori et al.   INFLAMMATION RESEARCH

Naringenin ameliorates daunorubicin induced nephrotoxicity by mitigating AT1R, ERK1/2-NFκB p65 mediated inflammation

(2015) Vengadeshprabhu Karuppagounder et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Naringenin Inhibits UVB Irradiation-Induced Inflammation and Oxidative Stress in the Skin of Hairless Mice

(2015) Renata M. Martinez et al.   JOURNAL OF NATURAL PRODUCTS

Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice

(2015) Cássia Calixto-Campos et al.   JOURNAL OF NATURAL PRODUCTS

Bosentan, a mixed endothelin receptor antagonist, inhibits superoxide anion-induced pain and inflammation in mice

(2015) Karla G. G. Serafim et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Naringenin neutralises oxidative stress and nerve growth factor discrepancy in experimental diabetic neuropathy

(2015) Salim S. Al-Rejaie et al.   NEUROLOGICAL RESEARCH

Superoxide anion-induced pain and inflammation depends on TNFα/TNFR1 signaling in mice

(2015) Fabiane Y. Yamacita-Borin et al.   NEUROSCIENCE LETTERS

Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction

(2015) Fenqin Chen et al.   PLoS One

Naringenin attenuates CCl4-induced hepatic inflammation by the activation of an Nrf2-mediated pathway in rats

(2014) Mohammad Ali Esmaeili et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Oxidative/Nitrosative Stress and Immuno-inflammatory Pathways in Depression: Treatment Implications

(2014) George Anderson et al.   CURRENT PHARMACEUTICAL DESIGN

The Transcription Factor Nrf2 Is a Therapeutic Target against Brain Inflammation

(2014) N. G. Innamorato et al.   JOURNAL OF IMMUNOLOGY

Naringenin confers protection against oxidative stress through upregulation of Nrf2 target genes in cardiomyoblast cells

(2014) Tharmarajan Ramprasath et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Role of naringenin in protection against diabetic hyperalgesia and tactile allodynia in male Wistar rats

(2014) Parisa Hasanein et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice

(2013) D.A.C. Magro et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Protective effect of naringenin against experimental colitis via suppression of Toll-like receptor 4/NF-κB signalling

(2013) Wei Dou et al.   BRITISH JOURNAL OF NUTRITION

IL-33/ST2 signalling contributes to carrageenin-induced innate inflammation and inflammatory pain: role of cytokines, endothelin-1 and prostaglandin E2

(2013) AC Zarpelon et al.   BRITISH JOURNAL OF PHARMACOLOGY

Up-down Regulation of HO-1 and iNOS Gene Expressions by Ethyl Pyruvate via Recruiting p300 to Nrf2 and Depriving It from p65

(2013) Seung-Woo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium

(2013) Ratana Lim et al.   MOLECULAR HUMAN REPRODUCTION

Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway

(2013) Haiyan Lou et al.   NEUROPHARMACOLOGY

Analgesic activity of piracetam: Effect on cytokine production and oxidative stress

(2013) Suelen A. Navarro et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1

(2012) Siyu Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Dietary Flavonoid Naringenin Induces Regulatory T Cells via an Aryl Hydrocarbon Receptor Mediated Pathway

(2012) Hsi-Kai Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Neuroprotective effect of naringenin is mediated through suppression of NF-κB signaling pathway in experimental stroke

(2012) S.S. Raza et al.   NEUROSCIENCE

Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes

(2012) S.-J. Moon et al.   OSTEOARTHRITIS AND CARTILAGE

Endothelin receptor antagonist attenuates oxidative stress in a neonatal sepsis piglet model

(2012) Tatenobu Goto et al.   PEDIATRIC RESEARCH

Anti-inflammatory role of naringenin in rats with ethanol induced liver injury

(2012) Jayachitra Jayaraman et al.   TOXICOLOGY MECHANISMS AND METHODS

Roles of reactive oxygen and nitrogen species in pain

(2011) Daniela Salvemini et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anti-inflammatory and Antifibrotic Effects of Naringenin in Diabetic Mice

(2011) Shih-Jei Tsai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Naringenin attenuates mucous hypersecretion by modulating reactive oxygen species production and inhibiting NF-κB activity via EGFR-PI3K-Akt/ERK MAPKinase signaling in human airway epithelial cells

(2011) J. Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Ethanol-induced HO-1 and NQO1 Are Differentially Regulated by HIF-1α and Nrf2 to Attenuate Inflammatory Cytokine Expression

(2010) Samantha M. Yeligar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant properties, radical scavenging activity and biomolecule protection capacity of flavonoid naringenin and its glycoside naringin: a comparative study

(2010) Monica Cavia-Saiz et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Naringenin more effectively inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression in macrophages than in microglia

(2010) Chia-Lun Chao et al.   NUTRITION RESEARCH

Morphine peripheral analgesia depends on activation of the PI3K /AKT/nNOS/NO/KATP signaling pathway

(2010) T. M. Cunha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Naringenin inhibits allergen-induced airway inflammation and airway responsiveness and inhibits NF-κB activity in a murine model of asthma

(2009) Ying Shi et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity

(2008) Michael M. Ndengele et al.   FASEB JOURNAL

Evidence that Cisplatin-induced Auditory Damage is Attenuated by Downregulation of Pro-inflammatory Cytokines Via Nrf2/HO-1

(2008) HongSeob So et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice

(2008) W. A. Verri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA