Mutations Designed by Ensemble Defect to Misfold Conserved RNA Structures of Influenza A Segments 7 and 8 Affect Splicing and Attenuate Viral Replication in Cell Culture

Title
Mutations Designed by Ensemble Defect to Misfold Conserved RNA Structures of Influenza A Segments 7 and 8 Affect Splicing and Attenuate Viral Replication in Cell Culture
Authors
Keywords
RNA structure, Microbial mutation, Influenza A virus, Influenza, Viral replication, Viral structure, Pseudoknots, Messenger RNA
Journal
PLoS One
Volume 11, Issue 6, Pages e0156906
Publisher
Public Library of Science (PLoS)
Online
2016-06-08
DOI
10.1371/journal.pone.0156906

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