Validation and Optimization of an Ex Vivo Assay of Intestinal Mucosal Biopsies in Crohn’s Disease: Reflects Inflammation and Drug Effects

C-Reactive Protein, Fecal Calprotectin and Stool Lactoferrin for Detection of Endoscopic Activity in Symptomatic Inflammatory Bowel Disease Patients: A Systematic Review and Meta-Analysis

(2015) Mahmoud H Mosli et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

(2015) Itay Raphael et al.   CYTOKINE

The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals

(2015) Peter J.K. van Meer et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ex vivo paracrine properties of cardiac tissue: Effects of chronic heart failure

(2015) Robert J. Boucek et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Toward a Personalized Medicine Approach to the Management of Inflammatory Bowel Disease

(2014) Mahmoud H Mosli et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Diagnosis and classification of Crohn's disease

(2014) Martin W. Laass et al.   AUTOIMMUNITY REVIEWS

Cytokines and cytokine receptors as immunotherapeutics: humble beginnings and exciting futures

(2014) Lisa M. Sedger et al.   CYTOKINE & GROWTH FACTOR REVIEWS

An update on medical management on Crohn’s disease

(2014) Andrea Affronti et al.   EXPERT OPINION ON PHARMACOTHERAPY

A CD3-Specific Antibody Reduces Cytokine Production and Alters Phosphoprotein Profiles in Intestinal Tissues From Patients With Inflammatory Bowel Disease

(2014) Anna Vossenkämper et al.   GASTROENTEROLOGY

Who Should Receive Biologic Therapy for IBD?

(2014) Jennifer Jones et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy

(2014) Raquel Franco Leal et al.   GUT

Distinctive Colonic Mucosal Cytokine Signature in New-Onset, Untreated Pediatric Crohn Disease

(2014) Francisco A. Sylvester et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Use of animal models in elucidating disease pathogenesis in IBD

(2014) Puja Vora Khanna et al.   Seminars in Immunopathology

Biologic therapies in inflammatory bowel disease

(2014) Lawrence B. Cohen et al.   Translational Research

Screening of budesonide nanoformulations for treatment of inflammatory bowel disease in an inflamed 3D cell-culture model

(2014) Fransisca Leonard   ALTEX-Alternatives to Animal Experimentation

Expression of IL-2, IL-17 and TNF-alpha in patients with Crohn's disease treated with anti-TNF antibodies

(2014) Lior H. Katz et al.   Clinics and Research in Hepatology and Gastroenterology

C-reactive protein in Crohn’s disease: how informative is it?

(2014) Fernando Magro et al.   Expert Review of Gastroenterology & Hepatology

Immunomodulators in Inflammatory Bowel Disease: An Emerging Role for Biologic Agents

(2013) Roslyn Kemp et al.   BIODRUGS

Anti-IL-12/23 in Crohn's Disease: Bench and Bedside

(2013) Lukas Niederreiter et al.   CURRENT DRUG TARGETS

Inflammatory bowel disease epidemiology

(2013) Johan Burisch et al.   CURRENT OPINION IN GASTROENTEROLOGY

Correlation Between the Endoscopic and Histologic Score in Assessing the Activity of Ulcerative Colitis

(2013) Bart Lemmens et al.   INFLAMMATORY BOWEL DISEASES

New targets for mucosal healing and therapy in inflammatory bowel diseases

(2013) M F Neurath   Mucosal Immunology

Insight into Crohn’s disease pathomorphology

(2012) Jonas Mudter et al.   ABDOMINAL IMAGING

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

(2012) Katerina Tsilingiri et al.   GUT

Epigenetic imprinting by commensal probiotics inhibits the IL-23/IL-17 axis in an in vitro model of the intestinal mucosal immune system

(2012) Darab Ghadimi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Epidemiology and Natural History of Inflammatory Bowel Diseases

(2011) Jacques Cosnes et al.   GASTROENTEROLOGY

Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy

(2011) Der-Yuan Chen et al.   ARTHRITIS RESEARCH & THERAPY

Proinflammatory cytokines underlying the inflammation of Crohnʼs disease

(2010) Warren Strober et al.   CURRENT OPINION IN GASTROENTEROLOGY

A Three-Dimensional Coculture of Enterocytes, Monocytes and Dendritic Cells To Model Inflamed Intestinal Mucosa in Vitro

(2010) Fransisca Leonard et al.   MOLECULAR PHARMACEUTICS

The Genetics of Crohn's Disease

(2009) Johan Van Limbergen et al.   Annual Review of Genomics and Human Genetics

Differential regulation of interleukin 17 and interferon   production in inflammatory bowel disease

(2009) L. Rovedatti et al.   GUT

Translating Inflammatory Bowel Disease Research into Clinical Medicine

(2009) Markus F. Neurath et al.   IMMUNITY

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

In vitro model to estimate gut inflammation using co-cultured Caco-2 and RAW264.7 cells

(2008) Takeshi Tanoue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation

(2008) Yinghua Xu et al.   CELL RESEARCH