Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis

Esculetin attenuates receptor activator of nuclear factor kappa-B ligand-mediated osteoclast differentiation through c-Fos/nuclear factor of activated T-cells c1 signaling pathway

(2015) Jong Min Baek et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sphingosine 1-phosphate counteracts insulin signaling in pancreatic β-cells via the sphingosine 1-phosphate receptor subtype 2

(2015) Lukasz Japtok et al.   FASEB JOURNAL

Periodontal inflammation and alveolar bone loss induced byAggregatibacter actinomycetemcomitansis attenuated in sphingosine kinase 1-deficient mice

(2015) H. Yu et al.   JOURNAL OF PERIODONTAL RESEARCH

FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans

(2015) Hong Yu et al.   Lipids in Health and Disease

Geniposide suppresses LPS-induced nitric oxide, PGE2 and inflammatory cytokine by downregulating NF-κB, MAPK and AP-1 signaling pathways in macrophages

(2014) Qinghai Shi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Bile acids are nutrient signaling hormones

(2014) Huiping Zhou et al.   STEROIDS

Biology of the RANKL–RANK–OPG System in Immunity, Bone, and Beyond

(2014) Matthew C. Walsh et al.   Frontiers in Immunology

Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation

(2013) G. Zhang et al.   BLOOD

Regulation of osteoclasts by membrane-derived lipid mediators

(2013) Tsukasa Oikawa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond

(2013) Gregory T. Kunkel et al.   NATURE REVIEWS DRUG DISCOVERY

Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D

(2013) J. Kikuta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and Gi-alpha dependent PI-3kinase signalling

(2012) Anta Ngkelo et al.   Journal of Inflammation-London

Fenretinide inhibited de novo ceramide synthesis and proinflammatory cytokines induced byAggregatibacter actinomycetemcomitans

(2012) Hong Yu et al.   JOURNAL OF LIPID RESEARCH

LPS and TNF-α induce expression of sphingosine-1-phosphate receptor-2 in human microvascular endothelial cells

(2012) Jing Du et al.   PATHOLOGY RESEARCH AND PRACTICE

Sphingosine-1-Phosphate Receptor-2 Function in Myeloid Cells Regulates Vascular Inflammation and Atherosclerosis

(2010) Athanasia Skoura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sphingosine 1-phosphate, a key mediator of the cytokine network: Juxtacrine signaling

(2010) Pu Xia et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice

(2010) Ana Olivera et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo

(2010) Masaru Ishii et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Role of Osteoclast-Associated Receptor in Osteoimmunology

(2010) K. Nemeth et al.   JOURNAL OF IMMUNOLOGY

Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network

(2009) Z. Tu et al.   GENOME RESEARCH

NFATc1: Functions in osteoclasts

(2009) Qingxiao Zhao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

(2009) Masaru Ishii et al.   NATURE

Osteoclast lineage and function

(2008) H. Kalervo Väänänen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cytokines That Promote Periodontal Tissue Destruction

(2008) Dana Graves   JOURNAL OF PERIODONTOLOGY