Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D

Combination therapy with eldecalcitol and alendronate has therapeutic advantages over monotherapy by improving bone strength

(2012) Sadaoki Sakai et al.   BONE

Effects of combined treatment with eldecalcitol and alendronate on bone mass, mechanical properties, and bone histomorphometry in ovariectomized rats: A comparison with alfacalcidol and alendronate

(2012) Masanori Sugimoto et al.   BONE

Higher Circulating Sphingosine 1-Phosphate Levels Are Associated with Lower Bone Mineral Density and Higher Bone Resorption Marker in Humans

(2012) Seung Hun Lee et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

(2012) Shigetomo Fukuhara et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone effects of vitamin D – Discrepancies between in vivo and in vitro studies

(2011) Tatsuo Suda et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effect of eldecalcitol, an active vitamin D analog, on hip structure and biomechanical properties: 3D assessment by clinical CT

(2011) Masako Ito et al.   BONE

A new active vitamin D3 analog, eldecalcitol, prevents the risk of osteoporotic fractures — A randomized, active comparator, double-blind study

(2011) Toshio Matsumoto et al.   BONE

Eldecalcitol

(2011) Mark Sanford et al.   DRUGS

Daily administration of eldecalcitol (ED-71), an active vitamin D analog, increases bone mineral density by suppressing RANKL expression in mouse trabecular bone

(2011) Suguru Harada et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow

(2010) Y. Maeda et al.   INTERNATIONAL IMMUNOLOGY

Odanacatib in the treatment of postmenopausal women with low bone mineral density: Three-year continued therapy and resolution of effect

(2010) John A Eisman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo

(2010) Masaru Ishii et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vitamin D, disease and therapeutic opportunities

(2010) Lori A. Plum et al.   NATURE REVIEWS DRUG DISCOVERY

Role of CX3CL1/Fractalkine in Osteoclast Differentiation and Bone Resorption

(2009) K. Koizumi et al.   JOURNAL OF IMMUNOLOGY

Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis

(2009) Masaru Ishii et al.   NATURE

Quantifying cellular interaction dynamics in 3D fluorescence microscopy data

(2009) Frederick Klauschen et al.   Nature Protocols

Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

(2008) Roger Bouillon et al.   ENDOCRINE REVIEWS