Anti-Breast Cancer Potential of Quercetin via the Akt/AMPK/Mammalian Target of Rapamycin (mTOR) Signaling Cascade

Anticarcinogenic action of quercetin by downregulation of phosphatidylinositol 3-kinase (PI3K) and protein kinase C (PKC) via induction of p53 in hepatocellular carcinoma (HepG2) cell line

(2015) Akhilendra Kumar Maurya et al.   MOLECULAR BIOLOGY REPORTS

Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion

(2015) Hui-Hui Cao et al.   Molecular Cancer

Modulation of PKC signaling and induction of apoptosis through suppression of reactive oxygen species and tumor necrosis factor receptor 1 (TNFR1): key role of quercetin in cancer prevention

(2015) Akhilendra Kumar Maurya et al.   TUMOR BIOLOGY

Targeting AMPK for cancer prevention and treatment

(2015) Weidong Li et al.   Oncotarget

Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells

(2015) Santhalakshmi Ranganathan et al.   PLoS One

Combined Resveratrol, Quercetin, and Catechin Treatment Reduces Breast Tumor Growth in a Nude Mouse Model

(2014) Alexander Schlachterman et al.   Translational Oncology

Quercetin reduces pluripotency, migration and adhesion of human teratocarcinoma cell line NT2/D1 by inhibiting Wnt/β-catenin signaling

(2014) Marija Mojsin et al.   Food & Function

Dietary grape polyphenol resveratrol increases mammary tumor growth and metastasis in immunocompromised mice

(2013) Linette Castillo-Pichardo et al.   BMC Complementary and Alternative Medicine

Quercetin prevents liver carcinogenesis by inducing cell cycle arrest, decreasing cell proliferation and enhancing apoptosis

(2013) María Laura Casella et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Site-Specific Anticancer Effects of Dietary Flavonoid Quercetin

(2013) Katrin Sak   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Resveratrol Induces Cell Cycle Arrest and Apoptosis in Malignant NK Cells via JAK2/STAT3 Pathway Inhibition

(2013) Ly Quoc Trung et al.   PLoS One

Resveratrol Inhibits the Epithelial Sodium Channel via Phopshoinositides and AMP-Activated Protein Kinase in Kidney Collecting Duct Cells

(2013) Kelly M. Weixel et al.   PLoS One

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

mTOR Signaling in Cancer Cell Motility and Tumor Metastasis

(2012) Hongyu Zhou et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration

(2012) Jonathan Michaud-Levesque et al.   EXPERIMENTAL CELL RESEARCH

The flavonoid paradox: conjugation and deconjugation as key steps for the biological activity of flavonoids

(2012) Francisco Perez-Vizcaino et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Grape Polyphenols Inhibit Akt/Mammalian Target of Rapamycin Signaling and Potentiate the Effects of Gefitinib in Breast Cancer

(2012) Linette Castillo-Pichardo et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Quercetin Inhibits Angiogenesis Mediated Human Prostate Tumor Growth by Targeting VEGFR- 2 Regulated AKT/mTOR/P70S6K Signaling Pathways

(2012) Poyil Pratheeshkumar et al.   PLoS One

Therapeutic Potential of Quercetin to Decrease Blood Pressure: Review of Efficacy and Mechanisms

(2012) Abigail J. Larson et al.   Advances in Nutrition

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Inhibition of the PI3K Pathway: Hope We Can Believe in?

(2010) M. S. van der Heijden et al.   CLINICAL CANCER RESEARCH

Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer

(2010) M. Bodmer et al.   DIABETES CARE

The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition

(2010) R. Vidya Priyadarsini et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The PI3K Pathway As Drug Target in Human Cancer

(2010) Kevin D. Courtney et al.   JOURNAL OF CLINICAL ONCOLOGY

Breast Cancer Metastasis: Challenges and Opportunities

(2009) J. Lu et al.   CANCER RESEARCH

Grape seed extract inhibits VEGF expression via reducing HIF-1  protein expression

(2009) J. Lu et al.   CARCINOGENESIS

Inhibition of mammary tumor growth and metastases to bone and liver by dietary grape polyphenols

(2009) Linette Castillo-Pichardo et al.   CLINICAL & EXPERIMENTAL METASTASIS

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

(2009) D. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quercetin inhibition of tumor invasion via suppressing PKC /ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells

(2008) C.-W. Lin et al.   CARCINOGENESIS

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways

(2008) Sonia Ramos   MOLECULAR NUTRITION & FOOD RESEARCH