Grape Seed Procyanidins and Cholestyramine Differentially Alter Bile Acid and Cholesterol Homeostatic Gene Expression in Mouse Intestine and Liver

Dietary procyanidins selectively modulate intestinal farnesoid X receptor-regulated gene expression to alter enterohepatic bile acid recirculation: elucidation of a novel mechanism to reduce triglyceridemia

(2016) Rebecca M. Heidker et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease

(2015) Daniel Jahn et al.   CYTOKINE & GROWTH FACTOR REVIEWS

A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis

(2015) Laura E. Downing et al.   PLoS One

Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal

(2014) Johannes Schmitt et al.   LIVER INTERNATIONAL

Bile Acid Signal-induced Phosphorylation of Small Heterodimer Partner by Protein Kinase Cζ Is Critical for Epigenomic Regulation of Liver Metabolic Genes

(2013) Sunmi Seok et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Colestilan decreases weight gain by enhanced NEFA incorporation in biliary lipids and fecal lipid excretion

(2013) Kanami Sugimoto-Kawabata et al.   JOURNAL OF LIPID RESEARCH

Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression

(2012) Dan Feng et al.   Lipids in Health and Disease

The Ileal Lipid Binding Protein Is Required for Efficient Absorption and Transport of Bile Acids in the Distal Portion of the Murine Small Intestine

(2012) Dana Praslickova et al.   PLoS One

Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins

(2011) Amanda A. Hayashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Bile acid sequestrants

(2011) Carolien Out et al.   CURRENT OPINION IN LIPIDOLOGY

Lowering Low-Density Lipoprotein Cholesterol: Statins, Ezetimibe, Bile Acid Sequestrants, and Combinations: Comparative Efficacy and Safety

(2009) Runhua Hou et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Fibroblast Growth Factor-19, a Novel Factor That Inhibits Hepatic Fatty Acid Synthesis

(2009) Sushant Bhatnagar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bile acid transporters

(2009) Paul A. Dawson et al.   JOURNAL OF LIPID RESEARCH

Dietary procyanidins enhance transcriptional activity of bile acid-activated FXRin vitroand reduce triglyceridemiain vivoin a FXR-dependent manner

(2009) Josep Maria Del Bas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary procyanidins lower triglyceride levels signaling through the nuclear receptor small heterodimer partner

(2008) Josep Maria Del Bas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Targeting bile-acid signalling for metabolic diseases

(2008) Charles Thomas et al.   NATURE REVIEWS DRUG DISCOVERY